Vessel Imaging Using Optical Coherence Tomography for Plaque Morphology and Vessel Fractional Flow Reserve
NCT ID: NCT06844942
Last Updated: 2025-02-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
200 participants
OBSERVATIONAL
2020-09-20
2029-01-31
Brief Summary
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Detailed Description
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The additional objectives encompass assessing the influence of age, sex, diabetes mellitus, renal dysfunction on the relationship between vFFR results and morphometric indices of intermediate coronary stenosis.
We hypothesized that in patients with intermediate grade coronary stenosis in chronic coronary syndrome a positive correlation exists between vFFR and the morphometric parameters associated with coronary stenosis.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Patients undergoing coronary angiogram in chronic coronary syndrome with intermediate stenosis.
Patients undergoing coronary angiogram due to chronic coronary syndrome with intermediate grade coronary stenosis.
vessel Fractional Flow Reserve
Optical coherence tomography and vessel fractional flow reserve evaluation of coronary arteries with intermediate to severe stenosis.
Interventions
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vessel Fractional Flow Reserve
Optical coherence tomography and vessel fractional flow reserve evaluation of coronary arteries with intermediate to severe stenosis.
Eligibility Criteria
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Inclusion Criteria
* Chronic coronary syndrome defined as presence of chest pain ranked 2-3 in the Canadian Cardiovascular Society classification or positive ischemia test (exercise test, single photon emission tomography (SPECT)
* Intermediate grade coronary stenosis of 40-80% assessed visually in coronary angiography and OCT examination The patient is willing to participate in the study and has provided a written informed consent
Exclusion Criteria
* Proximal left main lesion
* Ostial right coronary artery lesion
* Bypass of the assessed vessel
* Contraindications for adenosine administration
* Hemodynamic instability
* Heart insufficiency in New York Heart Association (NYHA) class IV scale
* Acute renal insufficiency
* Pregnancy
18 Years
ALL
No
Sponsors
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Medical University of Warsaw
OTHER
Responsible Party
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Mariusz Tomaniak
Mariusz Tomaniak, MD, PhD, Assoc. Prof.
Locations
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1st Department and Clinic of Cardiology, Medical University of Warsaw
Warsaw, Mazowieckie Voivodenship, Poland
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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VISION-FFR
Identifier Type: -
Identifier Source: org_study_id
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