Exposed Hypersensitive Dentin Treated With Fluoride Iontophoresis With Remineralizing Agents

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-07-01

Study Completion Date

2025-12-31

Brief Summary

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The goal of this clinical trial is to learn if the application of fluoride works to treat patients suffering from dentin hypersensitivity. It will also learn about the safety of using fluoride iontophoresis with Acidulated phosphate fluoride gel.

The main questions it aims to answer are:

Does the remineralizing agent have the ability to decrease dentin sensitivity?

Researchers will compare Fluoride Iontophoresis with Acidulated Phosphate Fluoride gel , Casein phosphopeptides-Amorphus calcium phosphate (CPP-ACP), nano-hydroxyapptite (NHAP) and -active glass in decreasing dentin hypersensitivity

.

Participants will:

* Application of remineralizing agent every 3 months
* Visit the dental clinic once every 3 months for checkups and tests

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Detailed Description

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Assess the efficacy of fluoride iontophoresis in remineralization in comparison with other ingredients.

Conditions

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Dentin Hypersensitivity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Fluoride Iontophoresis with Acidulated Phosphate Fluoride gel

assessmen of iontophoresis effect on flouride ions flush to remineralization of demineralized enamel .The treatment will be assessed and recorded using VAS score immediately after the intervention, 3 months, 6 months and one year later.

Group Type EXPERIMENTAL

Fluoride Iontophoresis with Acidulated Phosphate Fluoride

Intervention Type DRUG

Application of fluoride gel and activated with Iontophoresis electrical pole

remineralizing agents

All remineralizing agents (Casein phosphopeptides -Amorphus Calcium Phosphate, Nano-hydroxyapatite, and Bioactive glass).

Group Type ACTIVE_COMPARATOR

Remineralization with sodium fluoride varnish

Intervention Type DRUG

CASIN PHOSPHOPEPTIDE AMORPHOUS CALCIUM PHOSPHATE

Interventions

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Fluoride Iontophoresis with Acidulated Phosphate Fluoride

Application of fluoride gel and activated with Iontophoresis electrical pole

Intervention Type DRUG

Remineralization with sodium fluoride varnish

CASIN PHOSPHOPEPTIDE AMORPHOUS CALCIUM PHOSPHATE

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients within 35-60 years of age.
* Each patient has 4 or more exposed roots of posterior teeth having sensitivity.
* Good oral hygiene.
* Patients who will agree to the consent and will commit to the follow-up period.
* Patients will follow instructions during study time.
* Teeth that were vital.

Exclusion Criteria

* Patients with any systemic disease that may affect normal healing.
* Patient with bad oral hygiene, high caries index and high plaque index
* Patients participating in more than 1 dental study.
* Active carious lesions.
* Intrinsic and extrinsic stains.
* Any previous filling of selected teeth.
* Cracked and malformed teeth.

Minimum Eligible Age

35 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes