Endoscopy/Robotic Assisted Nipple Skin Sparing Mastectomy

NCT ID: NCT06823414

Last Updated: 2025-02-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

126 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-02-01

Study Completion Date

2034-04-01

Brief Summary

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Non-inferiority study of video-assisted (endoscopic or robotic) skin- and nipple-sparing mastectomy compared to open mastectomy. The feasibility of the technique, oncological safety and cosmetic results will be studied.

Detailed Description

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Conditions

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Breast Cancer Early Stage Breast Cancer (Stage 1-3) Breast Cancer Non-invasive Breast Cancer High Risk Breast Carcinoma

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Video assisted mastectomy

Patients with a video-assisted nipple skin sparing mastectomy

Video assisted mastectomy

Intervention Type OTHER

Nipple Skin sparing mastectomy assisted by endoscopic or robotic

Interventions

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Video assisted mastectomy

Nipple Skin sparing mastectomy assisted by endoscopic or robotic

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Women who require a mastectomy and who do not require skin reduction or resection are included. Women with both breast cancer and those at high risk for breast cancer are included.

Exclusion Criteria

* Sarcomas of the breast.
* Benign breast tumors.
* Prepectoral reconstruction with expansion.
* Impossibility to preserve the skin.
* Need for reduction pattern
* Inability to perform an MRI during follow-up (obesity, claustrophobia, etc.).
* Inability to complete the BREAST-Q™ questionnaire due to the patient's cognitive alterations.
* Refusal of the patient to participate in the study.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Alejandra García-Novoa

OTHER

Sponsor Role lead

Responsible Party

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Alejandra García-Novoa

Principal Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Breast Unit. First floor. Hospital Abente y Lago. Paseo del General Sir John Moore, 4

A Coruña, Galicia, Spain

Site Status RECRUITING

Countries

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Spain

Central Contacts

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Alejandra García Novoa, PhD MD

Role: CONTACT

981178000 ext. 296113

Facility Contacts

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Alejandra García Novoa, Ph.D

Role: primary

0034981178000 ext. 296158

Benigno Acea Nebril, Ph.D.

Role: backup

+34981178000 ext. 296158

References

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1. Acea-Nebril B, García-Novoa A, Cereijo-Garea C, Conde C, Bouzón A, Díaz C. Safety and Quality of Life in Women with Immediate Reconstruction with Polyurethane Implants after Neoadjuvant Chemotherapy: Outcomes from The Preq-20 Trial. Cancers 2023;15(4):1113. doi: 10.3390/cancers15041113. 2. Acea B, García A, García L, Díaz C, Bouzón A, Conde C. Immediate breast reconstruction by prepectoral polyurethane implant: Preliminary results of the prospective study PreQ-20. Cir Esp (Engl Ed) 2023;101(3):187-197. doi: 10.1016/j.cireng.2022.09.021. 3. Nakajima H, Sakaguchi K, Mizuta N, et al. Video-assisted total glandectomy and immediate reconstruction for breast cancer. Biomed Pharmacother 2002;56 Suppl 1:205s-8s. 4. Wei Ch, Lai HW. Endoscopic-assisted surgery in the management of breast cancer: 20 years review of trend, techniques and outcomes. Breast; 2019:46:144-156. doi: 10.1016/j.breast.2019.05.013. 5. Wei Ch, Lai HW. Evolution of minimal access breast surgery. Gland Surg 2019;8(6):784-793. doi: 10.21037/gs.2019.11.16. 6. Toesca A, Paradze N, Manconi A, Galimberti V, Intra M, Colleoni M et al. Robotic nipple-sparing mastectomy for the treatment of breast cancer: Feasibility and safety study. Breast 2017; Feb:31:51-56. doi: 10.1016/j.breast.2016.10.009. 7. Rathat G, Herlin C, Bonnel C, Captier G, Duraes M. Endoscopic Nipple-Sparing Mastectomy with Immediate Prepectoral Implant-Based Reconstruction: A Case Report Am J Case Rep 2019;20:1812-1816. doi: 10.12659/AJCR.919669.

Reference Type BACKGROUND

Other Identifiers

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VideoBreast-24

Identifier Type: -

Identifier Source: org_study_id

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