Detection of Muscle Quality in Children - Protocol for a Validation Study

NCT ID: NCT06792279

Last Updated: 2025-01-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-03-01

Study Completion Date

2026-03-31

Brief Summary

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The goal of this observational study is to evaluate the validity and reliability of ultrasound echo intensity (EI) as a diagnostic tool for assessing muscle quality in children aged 10-14 years, including normal-weight, obese, and trained young athletes. The main questions it aims to answer are:

Can EI reliably and accurately measure muscle quality in children when validated against gold-standard techniques like DXA and isokinetic dynamometry? What are the age-, sex-, and fitness-specific benchmarks for EI to differentiate between normal and pathological muscle quality?

Detailed Description

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Conditions

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Ultrasonography

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

• Generally healthy children

Exclusion Criteria

* Acute illnesses
* Chronic or acute diseases of the endocrine or musculoskeletal systems
* Post-traumatic conditions
Minimum Eligible Age

10 Years

Maximum Eligible Age

14 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Charles University, Czech Republic

OTHER

Sponsor Role lead

Responsible Party

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Michal Šteffl

ass. prof.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Faculty of Physical Education and Sport Charles University

Prague, Czech Republic, Czechia

Site Status

Countries

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Czechia

Central Contacts

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Michal Steffl, PhD

Role: CONTACT

+420778701882

Facility Contacts

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Michal Steffl

Role: primary

+420778701882

References

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Jandova T, Kinkorova I, Vetrovsky T, Mala J, Musilova E, Steffl M, Narici MV. Can ultrasound echo intensity assess muscle quality in children aged 10-14 years? Protocol for a cross-sectional validation study in Czech children. BMJ Open. 2025 Sep 26;15(9):e100495. doi: 10.1136/bmjopen-2025-100495.

Reference Type DERIVED
PMID: 41005786 (View on PubMed)

Other Identifiers

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EK 101/2024

Identifier Type: -

Identifier Source: org_study_id

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