Limb Salvage in Peripheral Arterial Trauma Patients

NCT ID: NCT06787495

Last Updated: 2025-01-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-09-01

Study Completion Date

2025-12-31

Brief Summary

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The aim of this study is to determine risk factors associated with failure of limb salvage in patients with periphral arterial injuries with or without attempts of revascularization.

Detailed Description

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Trauma to the vascular system can be devastating. Peripheral arterial traumatic injuries rarely occur in isolation, often complicated by bone fractures and nerve injuries. As a result of these complex injury patterns, vascular extremity trauma presents unique challenges to injury management and is associated with significant morbidity.

In all trauma- related injuries , trauma is now the third leading cause of death and number one cause of death in people between the ages of 1 and 44 years . Vascular injuries comprise 3% of all civilian trauma and have significant potential morbidity. Leg trauma is common. However, it is associated with a significant vascular injury.The high energy of crushing trauma can cause extensive tissue damage with detrimental outcome such as high morbidity and mortality.\[3\] Management of associated life-threatening injuries takes priority which might lead to delay in definitive vascular repairs with subsequent limb loss.The most important risk factor for early limb loss is failed revascularization which is time dependent

Conditions

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Trauma Patients

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Arterial repair

Arterial repair starting from simple repair or vein graft or synthetic graft

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* peripheral arterial trauma patients

Exclusion Criteria

* trauma patients with vascular injuries other than peripheral arteries
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mekhael Rezk Abd-Elmalak

OTHER

Sponsor Role lead

Responsible Party

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Mekhael Rezk Abd-Elmalak

Mekhael Rezk Abd-Elmalak Mesael

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Assiut university hospital

Asyut, , Egypt

Site Status

Countries

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Egypt

References

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McAndrew MP, Lantz BA. Initial care of massively traumatized lower extremities. Clin Orthop Relat Res. 1989 Jun;(243):20-9.

Reference Type BACKGROUND
PMID: 2721064 (View on PubMed)

Bondurant FJ, Cotler HB, Buckle R, Miller-Crotchett P, Browner BD. The medical and economic impact of severely injured lower extremities. J Trauma. 1988 Aug;28(8):1270-3. doi: 10.1097/00005373-198808000-00023.

Reference Type BACKGROUND
PMID: 3137367 (View on PubMed)

Mullenix PS, Steele SR, Andersen CA, Starnes BW, Salim A, Martin MJ. Limb salvage and outcomes among patients with traumatic popliteal vascular injury: an analysis of the National Trauma Data Bank. J Vasc Surg. 2006 Jul;44(1):94-100. doi: 10.1016/j.jvs.2006.02.052.

Reference Type BACKGROUND
PMID: 16828431 (View on PubMed)

Howe HR Jr, Poole GV Jr, Hansen KJ, Clark T, Plonk GW, Koman LA, Pennell TC. Salvage of lower extremities following combined orthopedic and vascular trauma. A predictive salvage index. Am Surg. 1987 Apr;53(4):205-8.

Reference Type BACKGROUND
PMID: 3579025 (View on PubMed)

Other Identifiers

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Arterial trauma patients

Identifier Type: -

Identifier Source: org_study_id

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