Outcomes of Traumatic Arterial Injuries in Upper vs. Lower Extremities

NCT ID: NCT05312489

Last Updated: 2022-04-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

65 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-06-01

Study Completion Date

2024-06-01

Brief Summary

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The purpose of this study is to identify and compare the causes of vascular trauma at the extremities, injury characteristics, types of vascular surgical interventions, and the outcomes of traumatic vascular injuries between the upper and lower extremities.

Detailed Description

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1. Primary patient assessment Patients will be clinically assessed on presentation, and resuscitation protocols will be initiated if signs of hypovolemic shock are present according to Advanced Trauma Life Support guidelines.
2. History and physical examination are the most important components of the diagnostic protocol The presence of hard signs of arterial injury

* Absent or diminished pulses
* Active haemorrhage
* Large, expanding, or pulsatile hematoma
* Bruit or thrill
* Distal ischemia is considered an indication for surgery, and no further specific investigative measures will be taken.

Soft signs of vascular trauma should be noted as well including
* Small, stable hematoma
* Unexplained hypotension
* History of haemorrhage that is no longer present
* Proximity of injury to major vessels
3. Investigations including:

* The use of a hand-held Doppler examination as a diagnostic aid
* Duplex US and CTA for imaging.
* Lab investigations: Complete blood picture, Coagulation profile and Kidney function tests.

Options of intervention:

All vascular trauma patients will be admitted for operative management and follow up. The specific surgical intervention will be determined by the vascular surgeon according to type, site, and extent of the injury, ranging from ligation of the injured vessel to vascular graft interposition.

An injury to a peripheral artery that does not result in complete transection can be repaired depending on luminal diameter with an interrupted or continuous suturing technique. A complete transection of a peripheral artery is first managed with minimal debridement back to healthy intima at both ends then an end-to-end anastomosis or with an interposition graft of autogenous vein or prosthetics arterial graft.

Conditions

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Vascular Trauma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Upper extremity arterial trauma

Vascular traumatic injuries of the arterial system of the upper limbs.

No interventions assigned to this group

Lower extremity arterial trauma

Vascular traumatic injuries of the arterial system of the lower limbs.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* All peripheral arterial injuries of one or more of the extremities.

Exclusion Criteria

* Vascular injuries limited to the venous system only.
* Vascular injuries limited to thoracic, abdominal, or neck vessels.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Abanoub Emad Mousa Daniel

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mohamed A Mubarak

Role: STUDY_DIRECTOR

Assiut University

Ashraf G Taha

Role: STUDY_DIRECTOR

Assiut University

Osman M Ahmed

Role: STUDY_DIRECTOR

Assiut University

Abanoub E Mousa

Role: PRINCIPAL_INVESTIGATOR

Assiut University

Central Contacts

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Abanoub E Mousa

Role: CONTACT

+20882056361

References

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Gallo LK, Ramos CR, Rajani RR, Benarroch-Gampel J. Management and Outcomes after Upper Versus Lower Extremity Vascular Trauma. Ann Vasc Surg. 2021 Oct;76:152-158. doi: 10.1016/j.avsg.2021.05.007. Epub 2021 Jun 18.

Reference Type BACKGROUND
PMID: 34153492 (View on PubMed)

Feliciano DV, Moore FA, Moore EE, West MA, Davis JW, Cocanour CS, Kozar RA, McIntyre RC Jr. Evaluation and management of peripheral vascular injury. Part 1. Western Trauma Association/critical decisions in trauma. J Trauma. 2011 Jun;70(6):1551-6. doi: 10.1097/TA.0b013e31821b5bdd. No abstract available.

Reference Type BACKGROUND
PMID: 21817992 (View on PubMed)

Feliciano DV, Moore EE, West MA, Moore FA, Davis JW, Cocanour CS, Scalea TM, McIntyre RC Jr. Western Trauma Association critical decisions in trauma: evaluation and management of peripheral vascular injury, part II. J Trauma Acute Care Surg. 2013 Sep;75(3):391-7. doi: 10.1097/TA.0b013e3182994b48.

Reference Type BACKGROUND
PMID: 23928739 (View on PubMed)

Huber GH, Manna B. Vascular Extremity Trauma. 2023 Apr 19. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK536925/

Reference Type BACKGROUND
PMID: 30725610 (View on PubMed)

Other Identifiers

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Vascular Trauma

Identifier Type: -

Identifier Source: org_study_id

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