Identification of Microcirculation After Surgical Treatment of Rupture of the Achilles Tendon

NCT ID: NCT01265004

Last Updated: 2012-11-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-12-31

Study Completion Date

2012-11-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This project investigates microcirculation in skin and tendon after a rupture of the Achilles tendon. Three different treatments are compared: stitches of the tendon, fibrin-glue and the combination of both.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This project investigates microcirculation in skin and tendon after a rupture of the Achilles tendon. Three different treatments are compared: stitches of the tendon, fibrin-glue and the combination of both.

Every method is long established and can be treated as clinical equal. So the surgical treatment is chosen randomly for each patient.

For this cause the microcirculation is registered by O2c, which works with measuring reflected lightwaves. It is strictly noninvasive and causes absolutely no pain for the patient. The measurement device consists of two small probes, which simply stick to the patient´s skin. There are nine measurements on this study: one before and one shortly after the surgery, followed by three measuring appointment every 6 hours (6,12,18,24 h post-op).Afterwards there are appointments planed after 12 days and 6 month. On the last appointment the patients are questioned according to established scores like AOFAS or VAS to register the functional outcome and level of pain.

Clinical parameters like time between rupture and surgical treatment, hospitalisation time, and form of anaesthesia are included to create comparable patient profiles. After 6 moths the last measurement appointment is stated, in which the clinical outcome is registered by Scores, e.g Mann-Whitney-Wilcoxon-Test.

This study is to detect any difference in wound heeling, re-rupture rate and functionality between these three methods.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Microcirculation Achilles Tendon Rupture

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

Functional outcome

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Stitches, rupture of achilles tendon

Patients, in who the achilles tendon rupture was treated with tendon surgery including a special way of stitching to preserve the sliding ability of the tendon.

Stitches

Intervention Type PROCEDURE

Surgical treatment of a rupture of the achilles tendon, in which both end are fastened with a U-forming stitching

Fibrin-glue, rupture of achilles tendon

Patients, who received a surgical treatment including a fixing of the tendon with fibrin-glue.

Fibrin-glue

Intervention Type PROCEDURE

Surgical treatment, in which both ends are glued together using a medical fibrin-containing glue

Stiches and Fibrin-glue

Patients, in who the achilles rupture was treated with stitches and fibrin-glue.

Stitches and Fibrin-glue

Intervention Type PROCEDURE

Surgical treatment, in which both ends of the ruptured tendon are fastened together with u-forming stitches as well as fibrin-glue

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Stitches

Surgical treatment of a rupture of the achilles tendon, in which both end are fastened with a U-forming stitching

Intervention Type PROCEDURE

Fibrin-glue

Surgical treatment, in which both ends are glued together using a medical fibrin-containing glue

Intervention Type PROCEDURE

Stitches and Fibrin-glue

Surgical treatment, in which both ends of the ruptured tendon are fastened together with u-forming stitches as well as fibrin-glue

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Acute rupture of the achilles tendon (on one or both sides)
* Older than 18 year of age
* Firmed letter of approval
* Patient speaks/understands German
* Planed surgical treatment
* No more than 48h after rupture

Exclusion Criteria

* No-traumatic rupture of the achilles tendon
* More than 48h after rupture
* No planed surgical treatment
* History of surgery on the injured leg
* Condition of diabetes mellitus
* Condition of peripheral artery occlusive disease
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

RWTH Aachen University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Hans-Christoph Pape, Univ-prof.MD

Role: STUDY_CHAIR

Chief of medicine

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Universal Hospital of the RWTH Aachen University

Aachen, North Rhine-Westphalia, Germany

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Germany

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

CTC-A10-26

Identifier Type: -

Identifier Source: org_study_id