Study of the Risk of Ischaemia Following the Creation of an Arteriovenous Fistula

NCT ID: NCT06297343

Last Updated: 2025-11-24

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 544 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2025-10-20
• Study Completion Date: 2027-12-31

Brief Summary

The purpose of this study is to identify functional vascular changes and clinical factors correlated with the occurrence of short- or medium-term hand ischaemia after arteriovenous fistula creation.

Detailed Description

This is a non-interventional, prospective, non-randomised, descriptive, single-centre study with no comparator.

The study population will be adult patients with chronic renal failure for whom an arteriovenous fistula has been planned.

Patients requiring the creation of an arteriovenous fistula by the surgeons at Hôpital Privé des Peupliers will be seen beforehand in the usual pre-operative consultation, during which the surgeon will explain the principle of the operation and the expected benefits/risks. On the day of surgery, patients will undergo the surgical procedure to create an arteriovenous fistula and will be discharged the same day. Patients will be reviewed during post-operative follow-up visits at 1, 6 and 12 months as in standard practice. All the data collected in the study were collected in routine medical practice.

Conditions

Renal Failure

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Adult patients with chronic renal failure

Adult patients with chronic renal failure for whom arteriovenous fistula creation is planned

Creation of an arteriovenous fistula

Intervention Type: PROCEDURE

Patients will undergo the surgical procedure to create an arteriovenous fistula and will be discharged the same day (outpatient care, or an overnight stay in hospital if they live a long way from the hospital, have multiple pathologies or are socially isolated). An arteriovenous fistula is created under local or general anaesthetic. On the day of the operation, the type of arteriovenous fistula created, the side of the arteriovenous fistula, the location of the arteriovenous fistula and the patency of the arteriovenous fistula will be collected.

Interventions

Creation of an arteriovenous fistula

Patients will undergo the surgical procedure to create an arteriovenous fistula and will be discharged the same day (outpatient care, or an overnight stay in hospital if they live a long way from the hospital, have multiple pathologies or are socially isolated). An arteriovenous fistula is created under local or general anaesthetic. On the day of the operation, the type of arteriovenous fistula created, the side of the arteriovenous fistula, the location of the arteriovenous fistula and the patency of the arteriovenous fistula will be collected.

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Age ≥ 18 years;
• Stage 5 chronic kidney disease, on dialysis or not on dialysis;
• Requiring the creation of an arteriovenous fistula;
• Membership of a social insurance scheme;
• Patient having been informed and having formulated his/her oral non-opposition to participate in the research.

Exclusion Criteria

• Contraindication to the proposed surgery ;
• Reduced life expectancy in the opinion of the investigator;
• Medical or biological conditions which, in the opinion of the investigator, could influence the interpretation of the results of the study or the safety of the patient;
• Patient uncooperative with protocol requirements or unable to attend scheduled visits to the centre;
• Other surgical or medical intervention planned during the study;
• Pregnant or likely to be pregnant (of childbearing age, without effective contraception) or breastfeeding;
• Participating in another clinical trial, or in a period of exclusion from another clinical trial;
• Patient under guardianship or deprived of liberty.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Euraxi Pharma

INDUSTRY

Sponsor Role: collaborator

GCS Ramsay Santé pour l'Enseignement et la Recherche

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Hôpital Privé des Peupliers

Paris, , France

Site Status: RECRUITING

Countries

France

Central Contacts

Viviane DUEDAL, MD

Role: CONTACT

v.duedal@gmail.com

6 70 80 18 98 ext. +33

Other Identifiers

2023-A02491-44

Identifier Type: -

Identifier Source: org_study_id