Stellate Ganglion Block for Preserving Arteriovenous Fistula in Hemodialysis Patients Undergoing Major Lower Limb Orthopedic Surgery
NCT ID: NCT06300658
Last Updated: 2025-02-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
50 participants
INTERVENTIONAL
2024-03-09
2025-02-28
Brief Summary
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Detailed Description
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Altered calcium and phosphor metabolism in CRF patients would also increase vascular reactivity. Stellate ganglion blockade (SGB) has been used for several years for both diagnosis and treatment of circulatory problems in upper extremity. Recently preemptive SGB has been used in prevention of radial artery spasm in coronary artery patients.
SGB increases blood flow and decrease vascular resistance in the arm. SGB prevents or ameliorates the reactivity of the muscular layer of the RA in response to both surgical manipulation during harvesting the artery and to the potent vasoconstrictor mediators released during surgery
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Stellate ganglion blockade
Patient will receive preemptive stellate ganglion blockade (SGB) just before spinal anesthesia.
Stellate ganglion block
Patient will receive preemptive stellate ganglion block (SGB) just before spinal anesthesia.
Control group
Patient will not receive preemptive stellate ganglion blockade (SGB).
No interventions assigned to this group
Interventions
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Stellate ganglion block
Patient will receive preemptive stellate ganglion block (SGB) just before spinal anesthesia.
Eligibility Criteria
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Inclusion Criteria
* Both sexes.
* American Society of Anesthesiologists (ASA) physical status III.
* Chronic renal failure (CRF) patients.
* Undergoing major lower limb orthopedic surgery.
Exclusion Criteria
* History of substance abuse.
* Ipsilateral brachial and radial artery stenosis.
* Allergy to local anesthetics.
* Cardiovascular and respiratory disorders.
* Coagulopathy.
* Use of vasoactive medications.
* Obesity (body mass index \>30 kg/m2).
* Smoking.
21 Years
75 Years
ALL
No
Sponsors
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Aswan University
OTHER
Responsible Party
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Ayman Mohamady Eldemrdash
Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Aswan University, Egypt
Locations
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Aswan University
Aswān, Aswan Governorate, Egypt
Countries
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Central Contacts
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Facility Contacts
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References
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Eldemrdash AM, Hammad SS, Hemaida TS, Dardeer TT, Mohsen AA, Fathy AK, Shams GH. Stellate ganglion block for preserving arteriovenous fistula in hemodialysis patients undergoing major lower limb orthopedic surgeries: randomized control trial. BMC Anesthesiol. 2025 May 31;25(1):277. doi: 10.1186/s12871-025-03150-7.
Other Identifiers
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900/2/24
Identifier Type: -
Identifier Source: org_study_id
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