A Study to Investigate Effects of Ocrelizumab Treatment on Neurofilament Light Chain (NfL) Levels and Participant Satisfaction in Participants With Multiple Sclerosis (MS)
NCT ID: NCT06780150
Last Updated: 2025-11-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
842 participants
OBSERVATIONAL
2024-09-26
2028-03-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Ocrelizumab
Participants who are receiving ocrelizumab, SC injection, for the first time as part of their routine MS therapy at physician's discretion in accordance with local clinical practice and/or labeling will be observed for treatment satisfaction with SC injection for up to 12 months.
Ocrelizumab
Ocrelizumab will be administered as SC injection as per discretion of the treating physician in accordance with local clinical practice and local labeling.
Interventions
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Ocrelizumab
Ocrelizumab will be administered as SC injection as per discretion of the treating physician in accordance with local clinical practice and local labeling.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* RMS and PPMS participants diagnosed according to the McDonald criteria of 2017
* First treatment during the course of MS therapy with ocrelizumab SC according to the local prescribing information, regardless of the reason for starting treatment with ocrelizumab
Exclusion Criteria
* Prior or simultaneous participation in CONFIDENCE or MoOzaRt (ISRCTN55332718) non interventional study (NIS) at the same study site
* Prior treatment with rituximab (MabThera®) or ublituximab (Briumvi®)
* Severe psychiatric disability
* Pregnant women
18 Years
ALL
No
Sponsors
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Hoffmann-La Roche
INDUSTRY
Responsible Party
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Principal Investigators
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Clinical Trials
Role: STUDY_DIRECTOR
Hoffmann-La Roche
Locations
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Uniklinik RWTH Aachen
Aachen, , Germany
Neuropraxis im Stadtpalais Dres. Ulzheimer/Herröder/Wessig GbR
Aschaffenburg, , Germany
Neurologie Bad Soden
Bad Soden, , Germany
Neurologische Praxis - Kallmann Neurologie - mszb
Bamberg, , Germany
Neurologisches Facharztzentrum Berlin am Sankt Gertrauden-Krankenhaus
Berlin, , Germany
NEUROZENTRUM tempelhof.berlin
Berlin, , Germany
Praxis Dr. Said Masri
Berlin, , Germany
Jüdisches Krankenhaus Berlin
Berlin, , Germany
NeuroZentrum Zehlendorf Dr. Ringel und Dr. Scherer
Berlin, , Germany
Neurologisches Zentrum für Bewegungsstörungen und Diagnostik
Berlin, , Germany
St. Josef-Hospital
Bochum, , Germany
Dres. Lippert/Kausch
Bogen, , Germany
Krankenhaus Buchholz Abt. Neurologie
Buchholz, , Germany
Neuropraxis Celle: Praxis für Neurologie & Psychatrie
Celle, , Germany
Praxisgemeinschaft Dres. Sylke Domke und Vasil Gjaurov
Chemnitz, , Germany
NeuroMed Campus Neurologische Gemeinschaftspraxis am St. Elisabeth Krankenhaus
Cologne, , Germany
Gemeinschaftspraxis Dr. med. Josef Leclaire und Dr. med. Thomas Rotermund
Dortmund, , Germany
Gemeinschaftspraxis für Neurologie
Düsseldorf, , Germany
Universitätsklinikum Düsseldorf
Düsseldorf, , Germany
Gemeinschaftspraxis für Neurologie und Psychiatrie, Psychotherapie
Eltville, , Germany
NeuroCentrum Odenwald
Erbach/Odenwald, , Germany
Universitätsklinikum Erlangen, Neurologische Klinik
Erlangen, , Germany
Zentrum für ambulante Neurologie / Praxis Knorn Landefeld Friedrich
Essen, , Germany
Praxis für Neurologie, Nervenheilkunde & Neurochirurgie
Forchheim, , Germany
Universitätsklinikum Freiburg, Klinik für Neurologie und Neurophysiologie
Freiburg im Breisgau, , Germany
Neurologie & Psychiatrie Gladenbach - MS-Zentrum
Gladenbach, , Germany
Neurologische Praxis Eppendorf
Hamburg, , Germany
Neurologische Praxis
Hanover, , Germany
Oberhavel Kliniken GmbH, Klinik Hennigsdorf, Neurologie
Hennigsdorf, , Germany
Praxis Dr. Hospely
Herford, , Germany
Klinikum Ibbenbüren gmbH
Ibbenbueren, , Germany
Augustahospital Anholt;Neurologie
Isselburg, , Germany
Universitätsklinikum Jena, Klinik für Neurologie
Jena, , Germany
Arztpraxis Dr. med. Torsten Sühnel
Leipzig, , Germany
Neurologische Praxis Dr. Ehrlich
Leipzig, , Germany
Neurologie im Ulrichshaus Magdeburg
Magdeburg, , Germany
Universitätsklinikum Magdeburg
Magdeburg, , Germany
Neuroplus Dres. Lennart Thilmann/ Patrick Thilmann
Mannheim, , Germany
Universitätsklinikum Mannheim
Mannheim, , Germany
Universitätsklinikum Giessen und Marburg
Marburg, , Germany
Praxis Dr. Leussink
Meerbusch, , Germany
Neurologie am Preußenmuseum
Minden, , Germany
Neurologie München Nord
München, , Germany
Praxis für Neurologie und Psychiatrie am Prinzregentenplatz
München, , Germany
Neurologisch-psychiatrische Praxis im A4
Neu-Ulm, , Germany
Praxis Dr. med. Bergmann
Neuburg am Inn, , Germany
Neurologie Nürnberg-Eibach
Nuremberg, , Germany
Neurologie an der Hase
Osnabrück, , Germany
Facharztpraxis für Neurologie und Psychiatrie Dres Mattes/Stockert
Pforzheim, , Germany
Neurologisches Studienzentrum Artland
Quakenbrück, , Germany
Gemeinschaftspraxis für Neurologie
Regensburg, , Germany
Praxis Dr. Stienker-Fisse
Remscheid, , Germany
Neurologische Praxis Dr. Wagner
Schwetzingen, , Germany
Gemeinschaftspraxis für Neurologie, Psychiatrie und Psychotherapie
Siegen, , Germany
Praxis für Neurologie und Psychiatrie
Siegen, , Germany
EMSA - Zentrum für Neurologie?/?Psychiatrie?/?Neuroradiologie
Singen, , Germany
Gemeinschaftspraxis Dr. Wolfram von Pannwitz, MBA & Dr. med. Marie Perle Brinckmann
Steglitz, , Germany
Praxis Dr. med. Andreas Kowalik, Arzt für Neurologie und Psychiatrie
Stuttgart, , Germany
Universitätsklinikum Tübingen, Zentrum für Neurologie
Tübingen, , Germany
Nervenfachaerztliche Gemeinschaftspraxis Ulm
Ulm, , Germany
Neuropraxis München Süd
Unterhaching, , Germany
Praxis für Neurologie, Psychiatrie und Epileptologie
Weil der Stadt, , Germany
Praxis Dr. Michaela Krause
Wolfratshausen, , Germany
Heinrich-Braun-Krankenhaus Städtisches Klinikum
Zwickau, , Germany
Inselspital-Universitaetsspital Bern
Bern, , Switzerland
Countries
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Central Contacts
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Reference Study ID Number: ML45551 https://forpatients.roche.com/
Role: CONTACT
Other Identifiers
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ML45551
Identifier Type: -
Identifier Source: org_study_id
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