Surgical Strategy for Head and Neck Adenoid Cystic Cancer

NCT ID: NCT06778915

Last Updated: 2025-01-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

309 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-01-01

Study Completion Date

2024-08-30

Brief Summary

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To investigate the relationship between surgical margins and outcomes across different tumor stages, in order to provide evidence and guidance for refining stage-specific surgical approaches.

Detailed Description

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Adenoid cystic carcinoma of the head and neck (HNACC) presents unique surgical challenges due to its propensity for perineural spread and proximity to critical craniofacial structures. While surgical resection remains the cornerstone of treatment, determining the optimal extent of resection to balance oncologic control and functional preservation requires further investigation. The investigator aimed to investigate the relationship between surgical margins and outcomes across different tumor stages, in order to provide evidence and guidance for refining stage-specific surgical approaches.

Conditions

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Adenoid Cystic Carcinoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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surgery

surgery

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* patients who underwent surgical resection with curative intent and PORT.

Exclusion Criteria

* underwent only biopsy, presented with distant metastases or second primary malignancies at initial diagnosis, had incomplete clinical or histopathologic data, or had histologic evidence of high-grade transformation.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

OTHER

Sponsor Role lead

Responsible Party

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Guopei Zhu

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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2024HNRT02

Identifier Type: -

Identifier Source: org_study_id

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