Comparison of the Incidence of Delirium Caused by Different Anesthetic Agents in Patients Undergoing Liver Transplantation

NCT ID: NCT06767579

Last Updated: 2025-01-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

350 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-10-24

Study Completion Date

2028-10-17

Brief Summary

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This study is a prospective observational study that analyzes the incidence of postoperative delirium in patients undergoing liver transplantation, based on the use of the inhalational anesthetic sevoflurane and the intravenous anesthetic propofol.

Detailed Description

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Conditions

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Hepatocellular Carcinoma Liver Cirrhosis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Sevoflurane Inhalation Anesthesia Group

Sevoflurane Inhalation Anesthesia Group in Liver Transplantation Patients

No interventions assigned to this group

Propofol Intravenous Anesthesia Group

Propofol Intravenous Anesthesia Group in Liver Transplantation Patients

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Adults aged 19 years and older
* Patients undergoing liver transplantation who are scheduled to receive anesthesia with the inhaled anesthetic sevoflurane or the intravenous anesthetic propofol.

Exclusion Criteria

* Individuals with hearing loss, cognitive impairment or obvious dementia, hepatic encephalopathy, or difficulty in communication.
* Diagnosed with neurological disorders (e.g., brain hemorrhage, stroke, dementia, Parkinson's disease, cognitive impairment, etc.).
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Yonsei University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Department of Anesthesiology and Pain Medicine Yonsei University College of Medicine

Seoul, , South Korea

Site Status RECRUITING

Countries

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South Korea

Facility Contacts

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Bon-Nyeo Koo, MD, PhD.

Role: primary

02-2227-7897

Other Identifiers

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4-2024-1084

Identifier Type: -

Identifier Source: org_study_id

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