Intraoperative Sedation and Postoperative Delirium

NCT ID: NCT02573558

Last Updated: 2016-04-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

855 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-10-31

Study Completion Date

2016-01-31

Brief Summary

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Delirium are common after orthopedic surgery in the elderly and are directly associated with loss of independence, reduction in the quality of life and increased mortality. The cause of postoperative delirium still remains unclear and may be multifactorial. The aim of this retrospective study is to examine prevalence of postoperative delirium according to the use of dexmedetomidine or propofol in elderly patients undergoing orthopedic surgery under regional anesthesia.

Detailed Description

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Conditions

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Orthopedics

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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DEX

patients who received dexmedetomidine during the operation

Dexmedetomidine

Intervention Type DRUG

PPF

patients who received propofol during the operation

Propofol

Intervention Type DRUG

Interventions

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Dexmedetomidine

Intervention Type DRUG

Propofol

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients who underwent orthopedic surgery under regional anesthesia
* age of 65 years or greater

Exclusion Criteria

* General anesthesia
* age \< 65 years
* central nervous system disease, including dementia and Parkinson's disease
* Patients who were not received sedation with propofol or dexmedetomidine during the operation
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Seoul National University Bundang Hospital

OTHER

Sponsor Role lead

Responsible Party

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Hyo-Seok Na

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Seoul National University Bundang Hospital

Seongnam-si, Gyeonggi-do, South Korea

Site Status

Countries

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South Korea

Other Identifiers

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B-1510/318-104

Identifier Type: -

Identifier Source: org_study_id

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