Personalized Education and Genetic Counseling to Increase Genetic Testing in Patients With a Known Family History of Pancreatic Cancer
NCT ID: NCT06744595
Last Updated: 2025-12-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ENROLLING_BY_INVITATION
NA
40 participants
INTERVENTIONAL
2025-02-12
2026-06-30
Brief Summary
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Detailed Description
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I. Perform Housing-Based Socioeconomic Status (HOUSES) index analysis on 500 patients with a first-degree relative diagnosed with pancreatic cancer to see if there is a correlation with the National Comprehensive Cancer Network (NCCN) criteria.
II. Offer 40 patients who did not have appropriate NCCN intervention the opportunity to have a genetic consultation (to consider genetic testing).
III. Survey patients on their knowledge and experiences of genetic testing based on family history and their decision-making when offered genetic counseling and testing.
OUTLINE:
Patients receive a personalized message through the Mayo portal (EPIC) with education on the NCCN guidelines for genetic counseling and an offer for standard of care (SOC) genetic counseling. Patients then receive pre-genetic test counseling on study. Patients may then optionally undergo SOC genetic testing and collection of blood or saliva samples as well as receive post-genetic test counseling on study.
Conditions
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Study Design
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NA
SINGLE_GROUP
HEALTH_SERVICES_RESEARCH
NONE
Study Groups
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Health services research (EPIC message, genetic counseling)
Patients receive a personalized message through EPIC with education on the NCCN guidelines for genetic counseling and an offer for SOC genetic counseling. Patients then receive pre-genetic test counseling on study. Patients may then optionally undergo SOC genetic testing and collection of blood or saliva samples as well as receive post-genetic test counseling on study.
Biospecimen Collection
Undergo collection of blood or salvia samples
Educational Intervention
Receive personalized EPIC message
Electronic Health Record Review
Ancillary studies
Genetic Counseling
Receive pre-genetic test counseling
Genetic Counseling
Receive post-genetic test counseling
Genetic Testing for Cancer Risk
Undergo SOC genetic testing
Survey Administration
Ancillary studies
Interventions
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Biospecimen Collection
Undergo collection of blood or salvia samples
Educational Intervention
Receive personalized EPIC message
Electronic Health Record Review
Ancillary studies
Genetic Counseling
Receive pre-genetic test counseling
Genetic Counseling
Receive post-genetic test counseling
Genetic Testing for Cancer Risk
Undergo SOC genetic testing
Survey Administration
Ancillary studies
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* First-degree relative with pancreatic cancer listed in the EPIC family history tool
* Active patient at Mayo Clinic Florida (MCF) (visits within 1/1/2023-12/31/2023 to Family Medicine and/or Gastroenterology and Hepatology)
* Patients with an active or past history of pancreatic cancer
* Patients who are pregnant or breastfeeding
18 Years
75 Years
ALL
Yes
Sponsors
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Mayo Clinic
OTHER
Responsible Party
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Principal Investigators
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Adrianna D. Clapp, MD
Role: PRINCIPAL_INVESTIGATOR
Mayo Clinic
Locations
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Mayo Clinic in Florida
Jacksonville, Florida, United States
Countries
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Related Links
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Mayo Clinic Clinical Trials
Other Identifiers
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NCI-2024-10177
Identifier Type: REGISTRY
Identifier Source: secondary_id
24-006906
Identifier Type: OTHER
Identifier Source: secondary_id
24-006906
Identifier Type: -
Identifier Source: org_study_id
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