Depression Among Cardiothoracic Surgery Patients in Baghdad

NCT ID: NCT06734169

Last Updated: 2025-03-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-04-20

Study Completion Date

2025-06-12

Brief Summary

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This observational study aims to estimate the prevalence and severity of depression among patients in the Cardiothoracic Surgery Ward in Baghdad City, Iraq, using a self-administered PHQ-9 questionnaire. The main questions it aims to answer are:

What is the prevalence of depression among cardiothoracic surgery patients? How is the severity of depression distributed within this group? Are there specific environmental or demographic factors associated with higher levels of depression?

Participants will:

Fill out the PHQ-9 in order to measure the severity of depressive symptoms at a specific moment in time.

Demographic and clinical variables such as age, gender, socioeconomic status, surgery type, comorbidities, and hospital stay length should be taken to look for a possible relationship with depression.

Detailed Description

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Depression is a common mental health condition that frequently coexists with chronic illnesses and surgical conditions, including cardiothoracic surgeries, significantly impacting recovery and long-term health outcomes. Studies have established a link between depressive symptoms and adverse postoperative results, including prolonged hospital stays, decreased quality of life, and increased mortality rates. In surgical populations, depression often remains undetected and untreated, exacerbating its negative effects on patient outcomes.

In Iraq, particularly in Baghdad, the prevalence of depression among cardiothoracic surgery patients is not well documented. The region's ongoing socio-economic challenges, coupled with limited access to mental health resources, pose additional barriers to adequate psychological care. Addressing these challenges requires robust data to inform targeted interventions.

The Patient Health Questionnaire-9 (PHQ-9) is a validated and widely used tool for screening depression in clinical and nonclinical populations It consists of nine questions that assess the frequency of depressive symptoms over the past two weeks, with scores ranging from 0 to 27. Diagnostic Cut-off: A score of ≥10 is often used as a threshold for identifying major depressive disorder with a high degree of sensitivity and specificity. Additionally, changes in PHQ-9 scores over time are used to evaluate the effectiveness of treatment. Its applicability in diverse populations makes it suitable for assessing depression among cardiothoracic surgery patients in Baghdad .

Baghdad is a region with limited local data on mental health, making it crucial to understand the mental health burden in surgical populations. This study aims to investigate the prevalence and severity of depression in this patient group, providing critical insights to bridge the gap in mental health care and improve surgical outcomes.

Conditions

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Depression

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* Patients admitted to the cardiothoracic surgery ward.
* Patients who are able to understand and provide informed consent.
* Patients who have the cognitive ability to complete the PHQ-9 questionnaire.

Exclusion Criteria

* Patients with a history of diagnosed psychiatric disorders other than depression.
* Patients who are critically ill or in a life-threatening condition and unable to participate.
* Patients who are unable to understand the PHQ-9 questionnaire due to language or cognitive barriers.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Al-Nahrain University

OTHER

Sponsor Role lead

Responsible Party

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Abdul-Ilah R. Khamis

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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College of Medicine - Al-Nahrain University

Baghdad, , Iraq

Site Status

Countries

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Iraq

Central Contacts

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Abdul-Ilah R. Khamis

Role: CONTACT

+9647838571013

Facility Contacts

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Abdul-Ilah R. Khamis

Role: primary

+9647838571013

Luma K Mohammed

Role: backup

+964770225676

References

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McCormick KM, Naimark BJ, Tate RB. Uncertainty, symptom distress, anxiety, and functional status in patients awaiting coronary artery bypass surgery. Heart Lung. 2006 Jan-Feb;35(1):34-45. doi: 10.1016/j.hrtlng.2005.08.002.

Reference Type BACKGROUND
PMID: 16426934 (View on PubMed)

Underwood MJ, Firmin RK, Jehu D. Aspects of psychological and social morbidity in patients awaiting coronary artery bypass grafting. Br Heart J. 1993 May;69(5):382-4. doi: 10.1136/hrt.69.5.382.

Reference Type BACKGROUND
PMID: 8518057 (View on PubMed)

Tully PJ, Baker RA. Depression, anxiety, and cardiac morbidity outcomes after coronary artery bypass surgery: a contemporary and practical review. J Geriatr Cardiol. 2012 Jun;9(2):197-208. doi: 10.3724/SP.J.1263.2011.12221.

Reference Type BACKGROUND
PMID: 22916068 (View on PubMed)

Morys JM, Bellwon J, Hofer S, Rynkiewicz A, Gruchala M. Quality of life in patients with coronary heart disease after myocardial infarction and with ischemic heart failure. Arch Med Sci. 2016 Apr 1;12(2):326-33. doi: 10.5114/aoms.2014.47881. Epub 2015 Jan 14.

Reference Type BACKGROUND
PMID: 27186176 (View on PubMed)

Tully PJ, Baker RA, Winefield HR, Turnbull DA. Depression, anxiety disorders and Type D personality as risk factors for delirium after cardiac surgery. Aust N Z J Psychiatry. 2010 Nov;44(11):1005-11. doi: 10.3109/00048674.2010.495053.

Reference Type BACKGROUND
PMID: 21034183 (View on PubMed)

Stenman M, Sartipy U. Depression Screening in Cardiac Surgery Patients. Heart Lung Circ. 2019 Jun;28(6):953-958. doi: 10.1016/j.hlc.2018.04.298. Epub 2018 May 16.

Reference Type RESULT
PMID: 29871802 (View on PubMed)

Manea L, Gilbody S, McMillan D. Optimal cut-off score for diagnosing depression with the Patient Health Questionnaire (PHQ-9): a meta-analysis. CMAJ. 2012 Feb 21;184(3):E191-6. doi: 10.1503/cmaj.110829. Epub 2011 Dec 19.

Reference Type RESULT
PMID: 22184363 (View on PubMed)

Sadik S, Bradley M, Al-Hasoon S, Jenkins R. Public perception of mental health in Iraq. Int J Ment Health Syst. 2010 Oct 11;4:26. doi: 10.1186/1752-4458-4-26.

Reference Type RESULT
PMID: 20937100 (View on PubMed)

Murphy BM, Elliott PC, Higgins RO, Le Grande MR, Worcester MU, Goble AJ, Tatoulis J. Anxiety and depression after coronary artery bypass graft surgery: most get better, some get worse. Eur J Cardiovasc Prev Rehabil. 2008 Aug;15(4):434-40. doi: 10.1097/HJR.0b013e3282fbc945.

Reference Type RESULT
PMID: 18677168 (View on PubMed)

Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001 Sep;16(9):606-13. doi: 10.1046/j.1525-1497.2001.016009606.x.

Reference Type RESULT
PMID: 11556941 (View on PubMed)

Other Identifiers

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011

Identifier Type: OTHER

Identifier Source: secondary_id

UNCOMIRB20241210C

Identifier Type: -

Identifier Source: org_study_id

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