Targeting Cervical Epidural Spinal Cord Stimulation for Functional Recovery
NCT ID: NCT06701422
Last Updated: 2025-11-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
36 participants
INTERVENTIONAL
2024-12-06
2026-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
BASIC_SCIENCE
NONE
Study Groups
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Arm 1 - Intraoperative Participants
Motor evoked responses responses (MEPs) to epidural electrical stimulation (EES) will be tested at cervical segments with and without myelopathy in participants with cervical myelopathy.
Intraoperative stimulation of the cervical spinal cord
The surgeon will place spinal cord electrodes on the epidural surface, with stimulation sites identified using preoperative MRI. Recruitment curves will be generated by systematically increasing the stimulation intensity across various parameter combinations, including frequency, pulse count, pulse shape, and electrode-specific properties such as size, separation, and arrangement.
Interventions
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Intraoperative stimulation of the cervical spinal cord
The surgeon will place spinal cord electrodes on the epidural surface, with stimulation sites identified using preoperative MRI. Recruitment curves will be generated by systematically increasing the stimulation intensity across various parameter combinations, including frequency, pulse count, pulse shape, and electrode-specific properties such as size, separation, and arrangement.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
ALL
No
Sponsors
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Congressionally Directed Medical Research Programs
FED
Columbia University
OTHER
Responsible Party
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Jason Carmel
Associate Professor
Locations
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Columbia University Irving Medical Center
New York, New York, United States
The Daniel and Jane Och Spine Hospital at NewYork-Presbyterian/Allen
New York, New York, United States
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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CDMRP-SC230233
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
AAAV1303
Identifier Type: -
Identifier Source: org_study_id
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