Correlation of Blood Serum Renalase and Microcirculation Obstruction in Patients with Acute Myocardial Infarction After Primary Percutaneous Coronary Intervention

NCT ID: NCT06669520

Last Updated: 2024-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-08-01

Study Completion Date

2025-10-01

Brief Summary

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This research will explore the association between blood serum renalase and microcirculation obstruction in patients with acute myocardial infarction (AMI) after primary percutaneous coronary intervention (PCI). The investigators aim to identify potential risk factors for microcirculation obstruction in AMI patients after PPCI.

Detailed Description

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Conditions

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Acute Myocardial Infarction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. Age ≥ 18 years;
2. STEMI symptom onset time \< 12 hours;
3. STEMI symptom onset time 12-48 hours with persistent ischemic symptoms, hemodynamic instability, or life-threatening ventricular arrhythmias;
4. High-risk NSTEMI;
5. Emergency PCI;
6. Voluntary informed consent.

Exclusion Criteria

1. Non-obstructive acute myocardial infarction;
2. Severe chronic kidney disease (defined as estimated glomerular filtration rate \< 20 mL/min per 1.73 m²);
3. Life expectancy \< 1 year;
4. Pregnant or planning to become pregnant;
5. Emergency PCI failure.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Third Xiangya Hospital of Central South University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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The Third Xiangya Hospital of Central South University

Changsha, Hunan, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Weihong Jiang

Role: CONTACT

(86)13786113632

Ye Chen

Role: CONTACT

(86)18674319338

Facility Contacts

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Weihong Jiang, Doctor

Role: primary

0086-13786113632

Ye Chen, Master

Role: backup

0086-18674319338

Weihong Jiang, Doctor

Role: backup

Ye Chen, Master

Role: backup

Other Identifiers

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K 24655

Identifier Type: -

Identifier Source: org_study_id

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