Sevoflurane Versus Propofol in Endovascular Coiling of Cerebral Aneurysm

NCT ID: NCT06666959

Last Updated: 2024-10-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-05-01

Study Completion Date

2024-05-08

Brief Summary

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The goal of this observational study is to learn about the anti-inflammatory effects of anesthetics on patients undergoing endovascular coiling of cerebral aneurysm. The main question it aims to answer is:

Does sevoflurane or propofol affect the inflammatory response in subarachnoid hemorrhage?

Participants already undergoing endovascular coiling of cerebral aneurysm will have their serum levels of inflammatory factors measured.

Detailed Description

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Conditions

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Propofol Sevoflurane

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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patients undergoing endovascular coiling of cerebral aneurysm in Tongji hospital

The present clinical study was carried out with the aim of determine whether the inflammatory effect differs when using propofol or sevoflurane anesthesia.

Anesthesia Agent

Intervention Type DRUG

intravenous anesthetic and inhalation anesthetic

Interventions

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Anesthesia Agent

intravenous anesthetic and inhalation anesthetic

Intervention Type DRUG

Other Intervention Names

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sevoflurane propofol

Eligibility Criteria

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Inclusion Criteria

* Consecutive patients aged 18 years and older presenting to the Tongji hospital for endovascular coiling of cerebral aneurysm were eligible for enrollment.

Exclusion Criteria

* have an endocrine system disease
* pregnancy
* have other brain disorders
* take drugs that alter endocrine hormones
* receive perioperative blood derivatives
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tongji Hospital

OTHER

Sponsor Role lead

Responsible Party

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mingxin zhu

associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of Neurosurgery

Wuhan, Hubei, China

Site Status

Countries

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China

Other Identifiers

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SW-001

Identifier Type: OTHER

Identifier Source: secondary_id

TJ-IRB20230413

Identifier Type: -

Identifier Source: org_study_id

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