Impact of a Proactive Strategy of General Practitioners on CRC Screening

NCT ID: NCT06664567

Last Updated: 2025-09-11

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 26260 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2026-01-01
• Study Completion Date: 2028-01-31

Brief Summary

In this registry-based cluster randomized controlled trial, we will assess the impact of a proactive strategy of general practitioners (GP) who will systematically provide screening kits of colorectal cancer (CRC) to all patients of even age (50, 52, 54...up to 74 years) versus usual practice where the eligible population receive an invitation letter to visit the general practitioner and receive the screening kit.

Detailed Description

Colorectal cancer is one of the leading causes of cancer and death in France in both men and women. The generalized screening rate is about 30% in France, far from the expected 65%, despite the fact that screening is free and a letter of invitation is sent to the individual's home, and despite the financial incentives provided to the practitioner. Different studies have looked for the causes of non-implementation by the individual: negligence, "dirty"; forgetfulness, and the practitioner: organizational problem, communication problem. A few intervention studies have been carried out with little success: sending the invitation to the individual's home, sending a letter of reminder, sending a letter of general information on screening to the practitioner, sending the list of patients who have not taken the test to the practitioner allows for a few percent improvement in screening. In this registry-based cluster randomized controlled trial, we will assess the impact of a proactive strategy of general practitioners who will systematically provide screening kits of colorectal cancer to all patients of even age (50, 52, 54 years...up to 74 years) versus usual practice where the eligible population receive an invitation letter to visit the general practitioner and receive the screening kit. The screening rate will be calculated for each arm at the end of the 2-year study with data from the health insurance.

Conditions

Colorectal Cancer

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: PROSPECTIVE

Study Groups

Systematic provision of screening tests by GPs

The general practitioner systematically delivers the screening kit with justification and modalities of realization at an even age between 50 and 74 years to the patient who comes to consult for whatever reason, who is at intermediate risk of colorectal cancer and who falls under the generalized screening. The practitioner is helped in his approach by an initial training in the identification of the age, delivery of a poster, a study sheet, stickers and goodies, sending a quarterly letter on the progress of the study and contact with the coordination team.

Colorectal cancer screening test

Intervention Type: BEHAVIORAL

delivery of colorectal cancer screening test by GP

Delivery of screening test according to GP's usual practice

the GP will issue the CRC screening kit in accordance with his/her usual practice.

Colorectal cancer screening test

Intervention Type: BEHAVIORAL

delivery of colorectal cancer screening test by GP

Interventions

Colorectal cancer screening test

delivery of colorectal cancer screening test by GP

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• medical practices in Aquitaine region and their visiting patients eligible for colorectal cancer screening individuals aged between 50 and 74 years at intermediate risk of colorectal cancer).

Exclusion Criteria

• medical practices with less than five individual eligible for colorectal cancer screening.
• visiting patients aged less than 50 years or more than 74 years or at high or very high risk of colorectal cancer.

• Minimum Eligible Age: 50 Years
• Maximum Eligible Age: 74 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University Hospital, Bordeaux

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Central Contacts

Christele BLANC-BISSON, Dr

Role: CONTACT

christele.blanc-bisson@u-bordeaux.fr

05 56 65 55 00 ext. +33

Pierre POULIZAC

Role: CONTACT

pierre.poulizac@chu-bordeaux.fr

05 57 82 08 49 ext. +33

Other Identifiers

CHUBX 2021/64

Identifier Type: -

Identifier Source: org_study_id