Role of GTR on Healing Outcome & Quality of Life in Combined Endo Perio Lesions With Communication
NCT ID: NCT06643663
Last Updated: 2025-01-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
30 participants
INTERVENTIONAL
2024-05-23
2025-12-23
Brief Summary
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Detailed Description
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1. To evaluate the impact of combined application of PRF-Medium and ACM membrane on healing outcomes in cases of apico-marginal defects with interproximal involvement with 2D periapical radiographs \& 3D CBCT imaging. SECONDARY OBJECTIVE
2. To evaluate and compare differences in quality of life of patients after periapical surgery with use of PRF-Medium and ACM membrane in cases of apico-marginal defects with interproximal involvement. PICO P(Population)- Patients with non-vital teeth and persistant chronic suppurative apical periodontitis with apico-marginal defects and interproximal involvement. I(Intervention)-Endodontic surgery followed by placement of PRF-Medium plug and ACM membrane. C(Comparison)-Endodontic surgery without using any plug and membrane. O(Outcome)- Periapical healing after surgery in both groups.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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Pt with apicomarginal defects & interproximal bone loss receiving GTR
Surgery performed using ACM membrane and PRF plug.
Endodontic Micro-Surgery
Surgery performed using ACM membrane and PRF plug in test group \& without membrane \& PRF in control group.
Pt with apicomarginal defects & interproximal bone loss without GTR
Surgery performed without ACM membrane and PRF plug.
Endodontic Micro-Surgery
Surgery performed using ACM membrane and PRF plug in test group \& without membrane \& PRF in control group.
Interventions
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Endodontic Micro-Surgery
Surgery performed using ACM membrane and PRF plug in test group \& without membrane \& PRF in control group.
Eligibility Criteria
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Inclusion Criteria
2. Patients with apico-marginal defects and deep pocket upto apex of tooth.
3. Failed primary root canal treatment.
4. Presence of interproximal bone loss.
5. Negative response to vitality test.
6. ASA-1 or ASA- 2 according to the classification of the American Society of Anesthesiologists)
Exclusion Criteria
2. Presence of root perforations
3. ASA-3 or ASA-4 according to the classification of the American Society of Anesthesiologists)
4. Presence of root resorption
5. Combined endodontic-periodontic lesions.
6. Pregnancy
16 Years
ALL
Yes
Sponsors
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Postgraduate Institute of Dental Sciences Rohtak
OTHER
Responsible Party
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Principal Investigators
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Dr, Sanjay Tewari, MDS
Role: STUDY_DIRECTOR
PGIDS, Rohtak, Haryana, 124001
Locations
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Pgids Rohtak
Haryāna, , India
Countries
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Central Contacts
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Facility Contacts
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SHWETA MITTAL, MDS
Role: backup
Other Identifiers
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Parichay Singhal
Identifier Type: -
Identifier Source: org_study_id
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