The Effects of Vegetable Preloading on Postprandial Glycemia, Insulinaemia and Gastric Emptying
NCT ID: NCT06640335
Last Updated: 2024-11-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
ACTIVE_NOT_RECRUITING
NA
24 participants
INTERVENTIONAL
2023-09-01
2025-09-19
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Food Containing Resistant Starch Type 4 and Postprandial Glycemic Response
NCT03844503
Post-prandial Glucose in Healthy Indian Subjects
NCT01999543
Effect of Resistant Starch Type 4 on Glycemia and Insulin Sensitivity in Young Adults
NCT00687960
Designer Functional Foods on Parameters of Metabolic and Vascular in Prediabetes
NCT02400450
Effect of a Plant-based Ingredient on Glucose Response
NCT02218528
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Results will demonstrate the mechanism of the impact of pre-loading nutrients on the digestion of glycemic carbohydrates. The goal is to eliminate the negative influence of glycemic carbohydrate consumption. Instead, to generate health benefits from dietary carbohydrates.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
CROSSOVER
OTHER
NONE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Control (All 24 participants)
Subjects consume 300 g of Russet Burbank mashed Potatoes
No interventions assigned to this group
Co-ingestion (All 24 participants)
Subjects co-ingest both (300 g mashed potatoes) and (200 g baby round spinach supplemented with canola oil) in the same time.
Co-ingestion
Subjects co-ingest both (300 g mashed potatoes) and (200 g baby round spinach supplemented with canola oil) in the same time.
0 min preload (meal sequence) (10 participants)
Subjects consume 200 g baby round spinach supplemented with canola oil first, then directly consume 300 g of mashed potatoes.
0 min preload
Subjects consume 200 g baby round spinach supplemented with canola oil first, then directly consume 300 g of mashed potatoes.
5 min preload (10 participants)
Subjects consume 200 g baby round spinach supplemented with canola oil first, wait 5 minutes, then consume 300 g of mashed potatoes.
5 min preload
Subjects consume 200 g baby round spinach supplemented with canola oil first, wait 5 minutes, then consume 300 g of mashed potatoes.
10 min preload (10 participants)
Subjects consume 200 g baby round spinach supplemented with canola oil first, wait 10 minutes, then consume 300 g of mashed potatoes.
10 min preload
Subjects consume 200 g baby round spinach supplemented with canola oil first, wait 10 minutes, then consume 300 g of mashed potatoes.
15 min preload (10 participants)
Subjects consume 200 g baby round spinach supplemented with canola oil first, wait 15 minutes, then consume 300 g of mashed potatoes.
15 min preload
Subjects consume 200 g baby round spinach supplemented with canola oil first, wait 15 minutes, then consume 300 g of mashed potatoes.
20 min preload (10 participants)
Subjects consume 200 g baby round spinach supplemented with canola oil first, wait 20 minutes, then consume 300 g of mashed potatoes.
20 min preload
Subjects consume 200 g baby round spinach supplemented with canola oil first, wait 20 minutes, then consume 300 g of mashed potatoes.
Spinach only /10 min preload (All 24 participants)
Subjects consume 200 g baby round spinach supplemented with canola oil first, wait 10 minutes, then consume 300 g of mashed potatoes.
Spinach only / 10 min preload
Subjects consume 200 g baby round spinach WITHOUT canola oil first, wait 10 minutes, then consume 300 g of mashed potatoes.
(Spinach + Canola oil) 10 min preload (All 24 participants)
Subjects consume 200 g baby round spinach WITHOUT canola oil first, wait 10 minutes, then consume 300 g of mashed potatoes.
10 min preload
Subjects consume 200 g baby round spinach supplemented with canola oil first, wait 10 minutes, then consume 300 g of mashed potatoes.
Canola oil only / 10 min preload (All 24 participants)
Subjects consume 20 g of canola oil first, wait 10 minutes, then consume 300 g of mashed potatoes.
Canola oil only / 10 min preload
Subjects consume 20 g of canola oil first, wait 10 minutes, then consume 300 g of mashed potatoes.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Co-ingestion
Subjects co-ingest both (300 g mashed potatoes) and (200 g baby round spinach supplemented with canola oil) in the same time.
0 min preload
Subjects consume 200 g baby round spinach supplemented with canola oil first, then directly consume 300 g of mashed potatoes.
5 min preload
Subjects consume 200 g baby round spinach supplemented with canola oil first, wait 5 minutes, then consume 300 g of mashed potatoes.
10 min preload
Subjects consume 200 g baby round spinach supplemented with canola oil first, wait 10 minutes, then consume 300 g of mashed potatoes.
15 min preload
Subjects consume 200 g baby round spinach supplemented with canola oil first, wait 15 minutes, then consume 300 g of mashed potatoes.
20 min preload
Subjects consume 200 g baby round spinach supplemented with canola oil first, wait 20 minutes, then consume 300 g of mashed potatoes.
Spinach only / 10 min preload
Subjects consume 200 g baby round spinach WITHOUT canola oil first, wait 10 minutes, then consume 300 g of mashed potatoes.
Canola oil only / 10 min preload
Subjects consume 20 g of canola oil first, wait 10 minutes, then consume 300 g of mashed potatoes.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Normal blood pressure \</=120/80 mmH
* Fasting blood glucose of \<5.6 mmol/l
* Able to provide written informed consent before participating in the study.
* Able to communicate adequately to comply with the requirements of the entire study, i.e., able to eat test meal and provide breath samples.
Exclusion Criteria
* Individuals with any metabolic diseases (such as diabetes, hypertension etc).
* Individuals with known glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency).
* Individuals with medical conditions and/or taking medications known to affect glycaemia (glucocorticoids, thyroid hormones, thiazide diuretics).
* Individuals who take any prescribed medication or dietary supplements which may interfere with the study measurements.
* Individuals who have any major organ dysfunction (eg. cardiovascular, respiratory, hepatic, renal, gastrointestinal) that may influence taste, olfaction, appetite, digestion, metabolism, absorption or elimination of test foods, nutraceutical or drug.
* Individuals with history of malabsorption due to mucosal disease, pancreatic disease, or other causes.
* Individuals with history of gastrointestinal disease or surgery (excludes appendectomy, hernia repair and anorectal disorders).
* Individuals who are allergic/intolerant to any of the test foods to be administered, or any of the following common food and ingredients: eggs, fish, milk, peanuts, tree nuts, shellfish, soya, wheat, gluten, cereal, fruits, dairy products, meat, vegetable, sugar and sweetener, natural food colourings or flavourings, sulphites etc.
* People who intentionally restrict food intake.
* People who consume excessive 13C rich products such as corn, sugar beet and pineapple.
* Individuals who partake in sports at the competitive and/or endurance levels
* Individuals who have any known chronic infection or known to suffer from or have previously suffered from or is a carrier of Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Human Immunodeficiency Virus (HIV).
* Individuals who is a study team member or an immediate family of any study team member.
* Individuals who consume Excessive alcohol: consuming \>/= 6 alcoholic drinks per week.
21 Years
40 Years
MALE
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Alliance for Potato Research and Education
OTHER
Singapore Institute of Food and Biotechnology Innovation
OTHER_GOV
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Amy Lin, PhD
Senior Principal Scientist I
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Amy Lin, PhD
Role: PRINCIPAL_INVESTIGATOR
Senior Principal Scientist I at Singapore Institute of Food and Biotechnology Innovation
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Clinical Nutrition Research Centre (CNRC)
Singapore, , Singapore
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
2021-095
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.