Effects of Allium Hookeri on Blood Glucose

NCT ID: NCT03330366

Last Updated: 2018-11-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-11-24

Study Completion Date

2018-03-31

Brief Summary

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The researchers investigated the anti-diabetic effects of Allium hookeri root extract for Korean prediabetic participants.

Detailed Description

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Allium hookeri root is widely consumed as a vegetable and herbal medicine in Asia. Although the antidiabetic activities of Allium hookeri have been documented in animal studies, the improved effects of Allium hookeri on human are not clear. Therefore, in this study, the researchers investigated whether Allium hookeri root extract could be effective in reducing the risk of type 2 diabetes in individuals with prediabetes.

Conditions

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PreDiabetes

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Allium hookeri extract

take two capsules per day (486 mg/day) for 8 weeks

Group Type EXPERIMENTAL

Allium hookeri extract

Intervention Type DIETARY_SUPPLEMENT

take two capsules per day (486 mg/day) for 8 weeks

Placebo

take two capsules per day for 8 weeks

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

take two capsules per day

Interventions

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Allium hookeri extract

take two capsules per day (486 mg/day) for 8 weeks

Intervention Type DIETARY_SUPPLEMENT

Placebo

take two capsules per day

Intervention Type DIETARY_SUPPLEMENT

Other Intervention Names

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AH

Eligibility Criteria

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Inclusion Criteria

* Fasting glucose 100\~126 mg/dl

Exclusion Criteria

* Significant variation in weight (more 10%) in the past 3 months
* Treatment by hypoglycemic and hypolipidemic drug therapy within the past three months
* Type 1 diabetes or HbA1c\>9.0%
* Cardiovascular disease
* Hypoglycemic agent, obesity medicine, and lipid lowering agent within past 6 months or blood sugar, obesity, and lipid improvement functional foods within past 2 monts
* Pregnancy or breast feeding
Minimum Eligible Age

20 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Chonbuk National University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Soo-Wan Chae

Principal Investigator, Clinical Trial Center for Functional Foods

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Park SH, Bae UJ, Choi EK, Jung SJ, Lee SH, Yang JH, Kim YS, Jeong DY, Kim HJ, Park BH, Chae SW. A randomized, double-blind, placebo-controlled crossover clinical trial to evaluate the anti-diabetic effects of Allium hookeri extract in the subjects with prediabetes. BMC Complement Med Ther. 2020 Jul 6;20(1):211. doi: 10.1186/s12906-020-03005-3.

Reference Type DERIVED
PMID: 32631388 (View on PubMed)

Other Identifiers

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CTCF2_2015_AH

Identifier Type: -

Identifier Source: org_study_id

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