Optimization of Management in Patients With Cardiovascular Disease After Lower Limb Joint Replacement

NCT ID: NCT06627933

Last Updated: 2024-10-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-15

Study Completion Date

2027-01-15

Brief Summary

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The goal of the study is to evaluate the frequency of cardiovascular and thromboembolic complications in patients with cardiovascular disease after lower limb joint replacement, the influence of known risk factors and strategies for perioperative prevention of thromboembolic complications on the frequency of cardiovascular complications and to develop approaches to optimize antithrombotic prevention tactics.

Detailed Description

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Conditions

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Thromboembolism Anticoagulant-induced Bleeding

Study Design

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Observational Model Type

ECOLOGIC_OR_COMMUNITY

Study Time Perspective

PROSPECTIVE

Study Groups

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Low thromboembolic risk

No interventions assigned to this group

Moderate thromboembolic risk

No interventions assigned to this group

High thromboembolic risk

No intervention

Intervention Type OTHER

No intervention

Interventions

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No intervention

No intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Informed consent
* Age older than 18 y.o.
* Cardiovascular disease
* Indications for planned lower limb joint replacement surgery

Exclusion Criteria

* Pregnancy
* Psychiatric disorders
* Decompensated heart failure or acute heart failure
* Known diagnosis of cancer
Minimum Eligible Age

18 Years

Maximum Eligible Age

95 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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I.M. Sechenov First Moscow State Medical University

OTHER

Sponsor Role lead

Responsible Party

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Olga Trushina

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University Hospital #1

Moscow, , Russia

Site Status RECRUITING

Countries

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Russia

Central Contacts

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Elena Okisheva, MD, PhD

Role: CONTACT

+79161162393

Facility Contacts

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Elena Okisheva, MD, PhD

Role: primary

+79161162393

References

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Okisheva EA, Mironova OI, Berdysheva MV, Pyatigorets ES, Krivova NP, Kurnosova AA, Elizarov MP, Smetanin SM, Lychagin AV, Fomin VV. [Relationship between the pain severity, use of non-steroidal anti-inflammatory drugs and blood pressure in elective large joint arthroplasty of the lower extremities]. Ter Arkh. 2023 Nov 3;95(9):751-756. doi: 10.26442/00403660.2023.09.202373. Russian.

Reference Type BACKGROUND
PMID: 38158917 (View on PubMed)

Okisheva EA, Trushina OY, Mamaeva MM, Redyanova EA, Zhazhieva AA, Chasova ID, Panferov AS, Bogdanov MM, Lychagin AV, Fomin VV. [Glucose metabolism disorders and hypoglycemic therapy in patients hospitalized for elective lower limb arthroplasty: a prospective, single-center, real-world study]. Ter Arkh. 2024 Jul 30;96(7):659-665. doi: 10.26442/00403660.2024.07.202780. Russian.

Reference Type RESULT
PMID: 39106508 (View on PubMed)

Other Identifiers

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11-23

Identifier Type: -

Identifier Source: org_study_id

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