Leveraging the Emergency Department (LEAD) Study

NCT ID: NCT06605534

Last Updated: 2026-02-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-10-29

Study Completion Date

2026-10-30

Brief Summary

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This is a pilot Type 1 Hybrid Effectiveness-Implementation Trial. The study will first examine reach in a non-traditional setting (the Emergency Department - ED) that uses an Electronic Health Record (EHR)-embedded Social Determinants of Health (SDoH) screening tool to identify lung screening-eligible patients for a tailored intervention to increase lung screening uptake. Reach is defined as the absolute number, proportion, and representativeness of individuals targeted for lung screening knowledge, awareness, and uptake. Then, a pilot trial will be conducted to examine the preliminary effectiveness of a tailored lung screening intervention compared to enhanced usual care to influence individual-level potential drivers of lung screening (health literacy, mistrust, stigma, fatalism, knowledge, lung screening health beliefs) and the ability to increase lung screening uptake among screening-eligible patients. Quantitative (Randomized Controlled Trial and EHR data) methods will be used for data collection and analysis to address the study aims.

Detailed Description

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Conditions

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Lung Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SCREENING

Blinding Strategy

NONE

Study Groups

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LungTalk Group

LungTalk is a novel theoretically grounded health educational tool that will be delivered via iPad and is an interactive computer-based program that includes audio, video and animation segments with scripts presented from a master content library in consideration of different ways people like to learn. Informed by our prior research, LungTalk tailors its content based on smoking status and perceived barriers. In prior work, LungTalk more than doubled Lung Cancer Screening (LCS) knowledge and health beliefs (p \< 0.01), and was associated with a significant increase in deciding to screen for lung cancer compared to control group; OR 1.99; 95% CI, 1.03, 3.85, p = 0.03.

Group Type EXPERIMENTAL

LungTalk

Intervention Type BEHAVIORAL

Tailored lung screening intervention

Non-tailored Lung Screening Pamphlet Group

Non-tailored Lung Screening Pamphlet is a non-tailored educational brochure, What is Lung Cancer Screening from the GO2 Foundation that will be emailed to the patient. This widely used educational standard of care is a 2-page reader-friendly non-tailored electronic brochure about risk and screening for lung cancer used in clinical and community settings.

Group Type ACTIVE_COMPARATOR

Non-tailored lung screening

Intervention Type OTHER

Non-tailored lung screening. It involves the addition of education to Social Determinants of Health (SDOH) screening and referral with patient navigation. Patients will be identified, and screened for SDOH needs using the UniteUs SDOH screener that is embedded in the Electronic Health Record (EHR), and connected to geographically-tailored resources (as described above under Arm 1). Participants will then be sent a non-tailored lung screening educational brochure via email to review that details lung cancer risk, lung screening facts, benefits, and potential harms. Within 48 hours, the Community Outreach and Engagement (COE) Patient Navigator will contact the patient to answer questions and provide navigation services as described above in Arm 1.

Interventions

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LungTalk

Tailored lung screening intervention

Intervention Type BEHAVIORAL

Non-tailored lung screening

Non-tailored lung screening. It involves the addition of education to Social Determinants of Health (SDOH) screening and referral with patient navigation. Patients will be identified, and screened for SDOH needs using the UniteUs SDOH screener that is embedded in the Electronic Health Record (EHR), and connected to geographically-tailored resources (as described above under Arm 1). Participants will then be sent a non-tailored lung screening educational brochure via email to review that details lung cancer risk, lung screening facts, benefits, and potential harms. Within 48 hours, the Community Outreach and Engagement (COE) Patient Navigator will contact the patient to answer questions and provide navigation services as described above in Arm 1.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Aged 50 years to 80 years
* Currently smoke cigarettes or quit smoking cigarettes within the past 15 years
* 20 pack-year smoking history
* Has never had lung cancer screening
* Able to provide informed consent
* Able to speak and understand English

Exclusion Criteria

* Diagnosed with lung cancer
* Has a history of having a lung cancer screening scan
* Unable to speak and understand English
Minimum Eligible Age

50 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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New Jersey Commission on Cancer Research

UNKNOWN

Sponsor Role collaborator

Hackensack Meridian Health

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Lisa Carter-Bawa, PhD

Role: PRINCIPAL_INVESTIGATOR

Hackensack Meridian Health

Locations

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Ocean Medical Center

Brick, New Jersey, United States

Site Status RECRUITING

John F. Kennedy Medical Center

Edison, New Jersey, United States

Site Status RECRUITING

Hackensack University Medical Center

Hackensack, New Jersey, United States

Site Status RECRUITING

Bayshore Medical Center

Holmdel, New Jersey, United States

Site Status RECRUITING

Southern Ocean Medical Center

Manahawkin, New Jersey, United States

Site Status RECRUITING

Jersey Shore University Medical Center

Neptune City, New Jersey, United States

Site Status RECRUITING

Palisades Medical Center

North Bergen, New Jersey, United States

Site Status RECRUITING

Old Bridge Medical Center

Old Bridge, New Jersey, United States

Site Status RECRUITING

Raritan Bay Medical Center

Perth Amboy, New Jersey, United States

Site Status RECRUITING

Riverview Medical Center

Red Bank, New Jersey, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Ana Guadalupe Vielma, PhD

Role: CONTACT

2018803400

Francis Valenzona

Role: CONTACT

2018803400

Facility Contacts

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Gia Nealy

Role: primary

201-880-3564

Gia Nealy

Role: primary

201-880-3564

Gia Nealy

Role: primary

201-880-3564

Gia Nealy

Role: primary

201-880-3564

Gia Nealy

Role: primary

201-880-3564

Gia Nealy

Role: primary

201-880-3564

Gia Nealy

Role: primary

201-880-3564

Gia Nealy

Role: primary

201-880-3564

Gia Nealy

Role: primary

201-880-3564

Gia Nealy

Role: primary

201-880-3564

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Other Identifiers

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Pro2024-0236

Identifier Type: -

Identifier Source: org_study_id

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