Project PLUS Lung Cancer Screening Promotion

NCT ID: NCT05937399

Last Updated: 2025-04-22

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 34 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-12-02
• Study Completion Date: 2024-12-31

Brief Summary

Project PLUS is a pilot study that aims to develop and obtain preliminary feasibility and efficacy data on an enhanced risk communication approach to promote lung cancer screening (LCS) intentions among screening-eligible individuals from environmentally burdened communities. Project PLUS will combine qualitative interviews to explore subject awareness regarding lung cancer risk and air pollution, barriers to LCS, and perceptions regarding risk communication messaging, develop a health education video, and a between-subjects experiment to compare Data from this pilot will form the basis for enhanced community engagement efforts and subsequent communication research to examine the effectiveness of incorporating the involuntary air pollution risk information in risk communication interventions. The long term goal is to reduce lung cancer burden and disparities among environmentally burdened communities within and outside of Philadelphia.

Detailed Description

Project PLUS is a pilot study that aims to develop and obtain preliminary feasibility and efficacy data on an enhanced risk communication approach to promote lung cancer screening (LCS) intentions among screening-eligible individuals from environmentally burdened communities. Project PLUS will combine qualitative interviews to explore subject awareness regarding lung cancer risk and air pollution, barriers to LCS, and perceptions regarding risk communication messaging, develop a health education video, and a between-subjects experiment to compare Data from this pilot will form the basis for enhanced community engagement efforts and subsequent communication research to examine the effectiveness of incorporating the involuntary air pollution risk information in risk communication interventions. The long term goal is to reduce lung cancer burden and disparities among environmentally burdened communities within and outside of Philadelphia.

This study is guided by the Health Belief Model and the Reasoned Action Approach.1 The study team will engage with two community partner organizations (Chester Environmental Partnership and Clean Water Action) to obtain feedback in implementing the study procedures and input on content for the health education video. The long-term goal is to improve LCS and reduce racial, ethnic, and socioeconomic disparities in lung cancer mortality.

Conditions

Lung Cancer

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: HEALTH_SERVICES_RESEARCH
• Blinding Strategy: SINGLE

Study Groups

Intervention Arm

This arm includes patients who view the integrated health video that provides information about both smoking and environmental risk.

Group Type: EXPERIMENTAL

Intervention video

Intervention Type: BEHAVIORAL

This intervention is an integrated health video provides individual (smoking) and environmental risk communication on intention to obtain lung cancer screening.

Control Video Arm

This arm includes patients who view the integrated health video that provides information ONLY about smoking risk.

Group Type: EXPERIMENTAL

Control video

Intervention Type: BEHAVIORAL

This intervention is an integrated health video provides individual (smoking) risk communication on intention to obtain lung cancer screening.

Interventions

Intervention video

This intervention is an integrated health video provides individual (smoking) and environmental risk communication on intention to obtain lung cancer screening.

Intervention Type: BEHAVIORAL

Control video

This intervention is an integrated health video provides individual (smoking) risk communication on intention to obtain lung cancer screening.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

1. Are ages 50 - 80 years;

2. Have a history of at least 20 cigarette pack-years, and who have quit within the past 15 years or are currently smoking;

3. Had a primary care visit at Penn Medicine within the last two years (2020-2021);

4. Have documented history of lung cancer screening or lung cancer

5. Are residing in one of 10 eligible zip codes;

6. Are English-speaking;

7. Are able to view the study videos;

8. Are able to participate in a video-conference interview using a HIPAA-compliant platform or able to participate in an interview over the phone.

Pilot trial participants will be eligible if they:

1. Are ages 50 - 80 years;

2. Are documented history of at least 20 cigarette pack-years, and who have quit within the past 15 years or are currently smoking;

3. Have no documented history of lung cancer screening or lung cancer;

4. Did not participate in patient interviews;

5. Had a primary care visit at Penn Medicine within the last two years (2020-2022);

6. Are residing in one of 10 eligible zip codes;

7. Are English-speaking;

8. Are able to view the study videos and complete an online survey.

2. Participated in patient interviews.

Exclusion Criteria

Patient interview participants are excluded if:

a. They are not eligible for lung cancer screening.

Pilot trial participants are excluded if they:

• Minimum Eligible Age: 50 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Abramson Cancer Center at Penn Medicine

OTHER

Sponsor Role: lead

Responsible Party

Katharine Rendle

Assistant Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Katharine Rendle, PhD,MSW,MPH

Role: PRINCIPAL_INVESTIGATOR

University of Pennsylvania

Andy Tan, PhD,MPH,MBA

Role: PRINCIPAL_INVESTIGATOR

University of Pennsylvania

Locations

University of Pennsylvania

Philadelphia, Pennsylvania, United States

Countries

United States

Other Identifiers

849953

Identifier Type: OTHER

Identifier Source: secondary_id

UPCC 03523

Identifier Type: -

Identifier Source: org_study_id