Myocardial Bridging in Obstructive Hypertrophic Cardiomyopathy

NCT ID: NCT06598995

Last Updated: 2024-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

968 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-01-01

Study Completion Date

2022-12-31

Brief Summary

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This study investigated the impact of myocardial bridging (MB) and its characteristics on preoperative atrial fibrillation and survival in patients with obstructive hypertrophic cardiomyopathy (oHCM). We recruited 968 consecutive patients with oHCM who underwent myectomy at our institution between January 2015 and December 2019, including 144 patients with MB and 824 patients without MB. All patients received angiography before surgery. The diagnosis of preoperative atrial fibrillation was based on 12-lead electrocardiography, 24-hour Holter electrocardiography, or in-hospital electrocardiogram monitoring, which was extracted from patients' medical records. Surgical details and follow-up data were also collected.

Detailed Description

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Conditions

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Myocardial Bridging Obstructive Hypertrophic Cardiomyopathy Atrial Fibrillation (AF)

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Obstructive hypertrophic cardiomyopathy who underwent septal myectomy

All patients underwent angiography and without other coronary artery disease.

Coronary artery bypass grafting or unroofing

Intervention Type PROCEDURE

Patients had an MB with \>75% compression degree would receive coronary artery bypass grafting, and those who underwent unroofing may had a depth of MB \< 5mm (whether deal with these MB with a depth \<5mm depends on the surgeon and the period time of patients received a surgery).

Interventions

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Coronary artery bypass grafting or unroofing

Patients had an MB with \>75% compression degree would receive coronary artery bypass grafting, and those who underwent unroofing may had a depth of MB \< 5mm (whether deal with these MB with a depth \<5mm depends on the surgeon and the period time of patients received a surgery).

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

\-

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Chinese Academy of Medical Sciences, Fuwai Hospital

OTHER

Sponsor Role lead

Responsible Party

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Changrong Nie

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Fuwai Hospital

Beijing, Please Select, China

Site Status

Countries

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China

Other Identifiers

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2022-GSP-GG-29

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

2022-1892

Identifier Type: -

Identifier Source: org_study_id

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