Effect of Radiofrequency Ablation in Patients With Ventricular Arrhythmia Undergoing CABG

NCT ID: NCT02991170

Last Updated: 2016-12-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

180 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-01-31

Study Completion Date

2018-12-31

Brief Summary

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Patients with myocardial infarction related potential malignant ventricular arrhythmia have high risk of sudden death. The aim of this clinical trial is evaluating therapeutic efficacy of unipolar or bipolar radiofrequency ablation in Coronary Artery Bypass Grafts (CABG) Surgery, which can reduce myocardial ischemia and block reentry circuits of ventricular arrhythmia at the same time. The observation indexes include the morbidity of potential malignant ventricular arrhythmia and major adverse cardiovascular events in mid-long-term after CABG surgery.

Detailed Description

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Conditions

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MI Related Malignant Ventricular Arrhythmia

Keywords

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myocardial infarction ventricular arrhythmia radiofrequency ablation Coronary Artery Bypass Grafts

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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control group

Patients with myocardial infarction related potential malignant ventricular arrhythmia undergoing Coronary Artery Bypass Grafts

Group Type ACTIVE_COMPARATOR

CABG

Intervention Type PROCEDURE

Patients with myocardial infarction related potential malignant ventricular arrhythmia undergoing Coronary Artery Bypass Grafts

interventional group

Patients with myocardial infarction related potential malignant ventricular arrhythmia undergoing unipolar or bipolar radiofrequency ablation and Coronary Artery Bypass Grafts at the same time

Group Type EXPERIMENTAL

unipolar or bipolar radiofrequency ablation+CABG

Intervention Type PROCEDURE

Patients with myocardial infarction related potential malignant ventricular arrhythmia undergoing unipolar or bipolar radiofrequency ablation and Coronary Artery Bypass Grafts at the same time

Interventions

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unipolar or bipolar radiofrequency ablation+CABG

Patients with myocardial infarction related potential malignant ventricular arrhythmia undergoing unipolar or bipolar radiofrequency ablation and Coronary Artery Bypass Grafts at the same time

Intervention Type PROCEDURE

CABG

Patients with myocardial infarction related potential malignant ventricular arrhythmia undergoing Coronary Artery Bypass Grafts

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* The patients have been receiving coronary artery bypass grafts from 2015.1-2017.12
* The patients had old myocardial infarction related potential malignant ventricular arrhythmia
* Anti-arrhythmic drug treatment is invalid
* All enrolled patients must being signed the informed consent

Exclusion Criteria

* Severe heart failure( ejection fraction under 35%)
* Patients with acute myocardial infarction
* Patients with ICD implanted
Minimum Eligible Age

45 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Xuanwu Hospital, Beijing

OTHER

Sponsor Role collaborator

Beijing Chao Yang Hospital

OTHER

Sponsor Role collaborator

Beijing Anzhen Hospital

OTHER

Sponsor Role lead

Responsible Party

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Yang Yu

Deputy Director of Cardiac Surgery, Principal Investigator,Clinical Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Xuanwu Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Beijing Chaoyang Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Beijing Anzhen Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Facility Contacts

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Dong Xu, doctor

Role: primary

Ying Tian, doctor

Role: primary

Yang Yu, doctor

Role: primary

Mingxin Gao, master

Role: backup

Other Identifiers

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XMLX201504

Identifier Type: -

Identifier Source: org_study_id