Mobile Intervention for Suicidal Thoughts

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-09-03

Study Completion Date

2027-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

One of the factors that contributes to suicide risk is what is known as a "suicidal belief system." This belief system is made up of several cognitions that been associated with suicide risk among military personnel. Modification of these cognitions may reduce suicidal thoughts and behaviors. The study team has developed a brief mobile intervention entitled the Mobile Intervention for Suicidal Thoughts (MIST) that uses evidence-based interpretation bias modification techniques to reduce these suicide cognitions. The goal of this project is to is to conduct a pilot trial of the MIST intervention to evaluate whether it is feasible an acceptable as an adjunct treatment for Veterans with suicidal ideation.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Developing a Mobile Intervention to Reduce Suicidal Cognitions in Veterans

NCT04881903

Suicide

COMPLETED NA

Executive Dysfunction & Suicide: An Exploration Of Risk Factors In Traumatically Brain Injured Veterans

NCT01118195

Traumatic Brain Injury (TBI) Suicidal Behavior

COMPLETED

A Novel Cognitive Remediation Intervention Targeting Poor Decision-making and Depression in Veterans at High Risk for Suicide: A Safe, Telehealth Approach During the COVID-19 Pandemic

NCT04952532

Major Depressive Disorder

COMPLETED NA

Crisis Response Planning in Military Personnel With Mild Traumatic Brain Injury

NCT07327567

Mild Traumatic Brain Injury Suicide Prevention Suicide Risk | Patient +2 more

NOT_YET_RECRUITING NA

Perceptual Retraining to Reduce Suicide Risk

NCT02845700

Perceptual Olfactory Bias

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

One of the factors that contributes to suicide risk is what is known as a "suicidal belief system." This belief system is made up of several cognitions, including hopelessness, thwarted belongingness, perceived burdensomeness, unlovability, unbearability, and unsolvability. These cognitions have all been associated with suicide risk among military personnel. Modification of these cognitions may reduce suicidal thoughts and behaviors. The study team has developed a brief mobile intervention entitled the Mobile Intervention for Suicidal Thoughts (MIST) that uses evidence-based interpretation bias modification techniques to reduce these suicide cognitions. The goal of this project is to is to conduct a pilot trial of the MIST intervention to evaluate whether it is feasible an acceptable as an adjunct treatment for Veterans with suicidal ideation.

The investigators will conduct a pilot randomized controlled trial (RCT), in which 50 Veterans with suicidal ideation will be randomized to either MIST plus Treatment as Usual and Safety Planning versus Treatment as Usual and Safety Planning. The central hypothesis is that Veterans will find MIST acceptable and will be willing to use it to reduce their suicidal thoughts.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Suicide

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

50 Veterans with suicidal ideation will be randomized to either MIST plus Treatment as Usual and Safety Planning versus Treatment as Usual and Safety Planning

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

The investigator and outcomes assessors will be blinded to the participant condition.

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Safety planning, treatment as usual, and MIST

Participants will get a safety plan, treatment as usual, and the MIST intervention.

Group Type EXPERIMENTAL

Safety planning

Intervention Type BEHAVIORAL

Safety planning (SP) is a single-session intervention that consists of developing a written list of individualized coping strategies and sources of support that can be used during a suicidal crisis.

Treatment as usual

Intervention Type BEHAVIORAL

This will include continued care with any of the Veterans' current providers. Study staff will also place appropriate referrals for Veterans, as needed (e.g., Trauma Recovery Program referrals for Veterans with PTSD, Sleep Psychology referrals for Veterans with insomnia). Participants will be encouraged to follow up with their providers' recommendations and treatment plans

MIST Intervention

Intervention Type BEHAVIORAL

This is a mobile intervention designed to target and modify suicidal cognitions. Veteran in this condition will be asked to use the intervention 5 times a week for 4 weeks.

Safety planning and treatment as usual

Participants will get a safety plan and treatment as usual.

Group Type ACTIVE_COMPARATOR

Safety planning

Intervention Type BEHAVIORAL

Safety planning (SP) is a single-session intervention that consists of developing a written list of individualized coping strategies and sources of support that can be used during a suicidal crisis.

Treatment as usual

Intervention Type BEHAVIORAL

This will include continued care with any of the Veterans' current providers. Study staff will also place appropriate referrals for Veterans, as needed (e.g., Trauma Recovery Program referrals for Veterans with PTSD, Sleep Psychology referrals for Veterans with insomnia). Participants will be encouraged to follow up with their providers' recommendations and treatment plans

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Safety planning

Safety planning (SP) is a single-session intervention that consists of developing a written list of individualized coping strategies and sources of support that can be used during a suicidal crisis.

Intervention Type BEHAVIORAL

Treatment as usual

This will include continued care with any of the Veterans' current providers. Study staff will also place appropriate referrals for Veterans, as needed (e.g., Trauma Recovery Program referrals for Veterans with PTSD, Sleep Psychology referrals for Veterans with insomnia). Participants will be encouraged to follow up with their providers' recommendations and treatment plans

Intervention Type BEHAVIORAL

MIST Intervention

This is a mobile intervention designed to target and modify suicidal cognitions. Veteran in this condition will be asked to use the intervention 5 times a week for 4 weeks.

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Veterans using the Durham VA Health Care System
* Endorsing suicidal ideation without intent in the last 30 days, established via C-SSRS
* Meet at least every 4 months with a mental health provider, established via chart review chart
* Can read at least 6th grade level material, established by their demonstrated ability to read the consent form and answer basic questions about it

Exclusion Criteria

* Currently in a period of active psychosis or mania, established via the SCID-5
* Currently meeting criteria for a moderate or severe alcohol or substance use disorder, established via the SCID-5
* Endorsing suicidal intent, established via C-SSRS
* Exhibit current prominent suicidal or homicidal ideation requiring immediate intervention
* Have used the MIST intervention before as part of another research study

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No