Mindfulness Training in Healthy Older Veterans

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-11-28

Study Completion Date

2019-07-31

Brief Summary

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Evidence shows the positive effects of Brain Health \& Wellness classes in younger individuals. The proposed study investigates the usefulness of these classes in older Veterans aged 50-85. We hope to show that such classes can lead to improvements in both thinking skills as well as stress levels.

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Detailed Description

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The expansion of the aging Veteran population, in addition to the frequent presence of comorbidities (e.g., PTSD and TBI) that exacerbate age-associated cognitive and health declines, has generated substantial interest in interventions that promote brain health in older Veterans. A growing body of evidence shows the positive effects of Brain Health \& Wellness classes on brain health in younger and middle-aged adults, thus training might be able to enhance brain health in older Veterans and offset age-related declines. Such training holds particular promise in enhancing areas of cognition that are especially susceptible to aging processes (e.g. attention and executive control), potentially through multiple mechanistic pathways. It is in many respects a cognitive exercise and may strengthen neural networks involved in such processes. Additionally, there is evidence for further facilitating brain health in other ways related to, for instance, altering the stress response. Currently, there is little information regarding the potential brain health benefits in older adults. As a first step to understanding these potential beneficial effects in Veterans, the aim of the proposed pilot study is to evaluate the acceptability, feasibility and potential efficacy of two Brain Health \& Wellness classes in healthy older Veterans through a randomized, controlled trial.

Conditions

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Aging

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Mindfulness

mindfulness/meditation/movement training

Group Type EXPERIMENTAL

Mindfulness-based Stress Reduction

Intervention Type BEHAVIORAL

mindfulness/meditation/movement training

Brain Health

Brain Health education class

Group Type ACTIVE_COMPARATOR

Brain Health

Intervention Type BEHAVIORAL

Brain Health Education

Interventions

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Mindfulness-based Stress Reduction

mindfulness/meditation/movement training

Intervention Type BEHAVIORAL

Brain Health

Brain Health Education

Intervention Type BEHAVIORAL

Other Intervention Names

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MBSR

Eligibility Criteria

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Inclusion Criteria

* Subjects will be Veterans age 50-85

Exclusion Criteria

* moderate or severe TBI
* active alcohol or drug dependence or abuse by DSM-5 criteria (within previous 30 days)
* positive urine drug screen for illicit substances
* history of schizophrenia
* ADHD
* learning disability
* dementia
* Mild Cognitive Impairment and/or other psychiatric disturbances not including PTSD and/or depression
* participants with a history of psychiatric hospitalization (last five years)
* suicide attempt (last five years)
* imminent risk for suicidal or homicidal behavior, or severe medical illness requiring treatment will be excluded
* subjects with a history of neurological diagnosis, e.g.,:

* brain tumor
* clinical stroke
* seizure
* Mini-Mental Status Exam score below 19 (suggesting moderate/severe cognitive impairment, a contraindication to MBSR participation) will be excluded

Minimum Eligible Age

50 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes