The Effect of Body Mass Index on Short-term Results of HTO
NCT ID: NCT06590818
Last Updated: 2024-09-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
50 participants
INTERVENTIONAL
2024-07-10
2025-07-10
Brief Summary
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Detailed Description
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Knee osteoarthritis (KOA) is a multi-etiological, chronic disabling disease that affects the entire knee joint, which is the most common site of involvement in OA. KOA is classified as primary or secondary depending on etiology. The pathogenesis of primary KOA is complex and involves numerous factors, such as mechanical stress, inflammation, metabolism, immunity and genetics, with age, genetics, body weight, sex and race being risk factors.
Diagnosis of knee osteoarthritis can be confirmed based on clinical and/or radiological features. The potential of a progressive disease can be prevented or decreased by earlier recognition and correction of associated factors.Obesity and alignment especially varus malalignment are recognized factors of a progressive disease. Both non pharmalogical as well as pharmacological modalities of treatment are useful in managing the symptoms of knee osteoarthritis. Surgery should be considered only in patients who do not respond to medical therapy.
Varus knee osteoarthritis is one of the most common knee diseases in clinical practice. Knee pain and limited range of motion seriously affect the patient's quality of life. However, there is need for further exploration into the prevention and treatment of postoperative complications following artificial joint replacement.
Osteotomy techniques such as high tibial osteotomy are primarily used for the treatment of KOA with varus and valgus deformities.
High body mass index is a risk factor for KOA. A previous study reported a 35% increase in KOA risk with every 5-unit increase in body mass index. This is primarily attributed to the fact that greater body weight increases the weight-bearing pressure of the knee joint, thereby increasing the probability of KOA
Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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varus knee osteoarthritis Group
About 50 patients had varus knee osteoarthritis underwent high tibial osteotomy (HTO)
High tibial osteotomy (HTO
To investigate the effect of body mass index (BMI) on the early efficacy of high tibial osteotomy (HTO) in the treatment of varus knee osteoarthritis
Interventions
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High tibial osteotomy (HTO
To investigate the effect of body mass index (BMI) on the early efficacy of high tibial osteotomy (HTO) in the treatment of varus knee osteoarthritis
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* No serious underlying medical disease
* Conservative treatment is ineffective and there is a willingness for surgery
* X-ray shows degeneration limited to the medial joint space (Ahlback grade ≥ grade II)
* Knee flexion range of motion \> 90°, varus deformity \< 15°, flexion contracture \< 5°.
* Clinical examination shows intact anterior cruciate ligament and collateral ligament, tenderness point is limited to the medial joint space, and the lateral compartment and patellofemoral joint are intact.
Exclusion Criteria
* severe obesity (BMI\>35 kg/m 2 ) or morbid obesity (obesity caused by diseases such as hypercortisolism and hypothyroidism, BMI≥30 kg/m 2 ).
40 Years
60 Years
ALL
No
Sponsors
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Al-Azhar University
OTHER
Egymedicalpedia
INDUSTRY
Responsible Party
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Principal Investigators
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Maysara Abdelhaleem Bayuomy, Assist.Prof
Role: STUDY_CHAIR
Orthopedic &Trauma surgery Department, Faculty of medicine, Al-Azhar University, Assiut
Locations
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Al-Azhar University hospitals
Asyut, , Egypt
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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Ahmed Ramadan Hammad
Identifier Type: -
Identifier Source: org_study_id
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