Assessing the Effectiveness and Safety of Pericapsular Nerve Group (PENG) Block in Hip Fracture Patients on Antithrombotic Therapy
NCT ID: NCT06582667
Last Updated: 2024-09-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
100 participants
INTERVENTIONAL
2024-09-17
2025-04-17
Brief Summary
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Detailed Description
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Group A (Antithrombotic Therapy Group): 50 Patients on continuous antithrombotic therapy will receive BENG block.
Group C (Control Group): 50 Patients without antithrombotic therapy will receive BENG block.
Intervention:
PENG Block: Standardized administration of the PENG block will be performed by experienced anesthesiologists for both groups using ultrasound device.
The patients will be subjected to standard monitoring and received nasal cannula oxygen (2 L/min). Midazolam (1-2 mg) will be administered intravenously for light sedation.
Under sterile conditions, a low-frequency curvilinear probe of ultrasound (SonoSite S-Nerve Machine, Fujifilm) is initially placed in a transverse plane over the anterior inferior iliac spine, and is then rotated parallel to the pubic ramus to obtain a short-axis view of the iliopsoas muscle and tendon lying on the ramus pubic adjacent to the iliopubic eminence. After skin infiltration with 1-3 mL 1% lidocaine, a 23 G, 70 mm insulated block needle is inserted in-plane in a lateral-to- medial direction to place the tip in the musculofascial plane between the psoas tendon and the pubic ramus. A total of 20 mL 0.5% bupivacaine (AstraZeneca, EGYPT) is injected slowly in 5 mL increments with intermittent aspiration and under constant ultrasound surveillance for adequate fluid spread. Thirty minutes after the block completion, standardized endotracheal general anesthesia is induced with propofol (2-2.5 mg/kg), fentanyl (0.5-1,5 μg/kg), and atracurium (0.5 mg/kg).maintenance of anesthesia is done with sevoflurane (2-2.5%) with o2and air 60:40% Antithrombotic Management: Clear protocols for managing antithrombotic therapy in Group A will be implemented, considering perioperative bleeding risk
Conditions
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Study Design
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RANDOMIZED
PARALLEL
HEALTH_SERVICES_RESEARCH
DOUBLE
Study Groups
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group A: PENG block in hip fracture with antithrombotic therapy
50 patients will receive US guided PENG block and on antithrombotic therapy in hip fracture
PENG block
US guided PENG block in hip fracture without anti thrombotic therapy
group C: PENG block in hip fracture without antithrombotic therapy
50 patients will receive US guided PENG block without antithrombotic therapy in hip fracture
PENG block
US guided PENG block in hip fracture without anti thrombotic therapy
Interventions
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PENG block
US guided PENG block in hip fracture without anti thrombotic therapy
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* diagnosis of hip fracture
* scheduled for surgical intervention within 48 hours
* Informed consent obtained.
Exclusion Criteria
* Contraindications to the PENG block
* inability to provide informed consent.
65 Years
85 Years
ALL
No
Sponsors
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Alexandria University
OTHER
Responsible Party
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Locations
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Faculty of Medicine
Alexandria, , Egypt
Countries
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Central Contacts
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Facility Contacts
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References
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Giron-Arango L, Peng PWH, Chin KJ, Brull R, Perlas A. Pericapsular Nerve Group (PENG) Block for Hip Fracture. Reg Anesth Pain Med. 2018 Nov;43(8):859-863. doi: 10.1097/AAP.0000000000000847.
Other Identifiers
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PENG block with antithrombotic
Identifier Type: -
Identifier Source: org_study_id
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