Patients With Acute Hip Fractures Will Receive Either the PENG Block or no Block Respectively.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-05-24

Study Completion Date

2022-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Hip fracture pain is often severe and traditionally managed by systemic opioids which have increased risk of side effects in frail elderly patients. Inadequately controlled pain may lead to delirium which increases mortality and morbidity. The overall aim of this RCT is to investigate the potential for improved pain relief accomplished by the addition of the PENG block to current standard practice of pre-operative analgesia (systemic morphine), compared to the control group, which involves no block (operator will still go through the motion as if performing a block) plus standard pre-operative analgesia.

The investigator hypothesize that the addition of a single shot PENG block at the side of hip fracture in addition to traditional systemic morphine provides good preoperative pain relief on movement and reduces the need for breakthrough opioid requirements. The investigator hypothesize that the interventional group dynamic pain score assessed at 30 minutes after the block compared to control group dynamic pain score at 30 minutes after the "block" will be at least a 3 point difference between the 2 groups .

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The PENG Block in Elective Hip Surgery and Its Effect on Postoperative Pain and Length of Stay.

NCT05056675

Pain, Postoperative

COMPLETED NA

Single Shot Fascia Iliaca Block vs Femoral Nerve Block for Analgesia for Surgical Fixation of Hip Fractures

NCT02330302

Hip Fracture

COMPLETED NA

Assessing the Effectiveness and Safety of Pericapsular Nerve Group (PENG) Block in Hip Fracture Patients on Antithrombotic Therapy

NCT06582667

Hip Fracture Antithrombotic Therapy PENG Block

NOT_YET_RECRUITING NA

MED90 of Ropivacaine for Peripheral Nerve Block on Posture-evoked Pain in Spinal Anesthesia Positioning

NCT04705974

Hip Fractures

UNKNOWN NA

Pericapsular Nerve Block Versus Propofol During Hip Fractures Surgery

NCT06631118

Difference in Reduction in Visual Analogue Score at 30 Minutes

NOT_YET_RECRUITING NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Specific Aim1: To determine difference in pain scores on movement (dynamic pain scores) in patients who receive the PENG block in the intervention group compared to no block in the control group at 30 minutes after performance of the block.

Specific Aim2: To determine if there is any difference in pain at rest between the intervention group and the control group, and if so, the magnitude of the difference in pain scores.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Hip Fractures

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Patient, nurses and CRC will be blinded. Rest of study team is not blinded.

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Control

Only standard care

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

Standard care

Intervention group

The PENG block was performed for intervention group with local anaesthetic solution composed of 20 ml of ropivacaine 0.5%.

Group Type EXPERIMENTAL

Ropivacaine 0.5% Injectable Solution

Intervention Type DRUG

Local anaesthetic solution composed of ropivacaine 0.5%(intervention group)

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Ropivacaine 0.5% Injectable Solution

Local anaesthetic solution composed of ropivacaine 0.5%(intervention group)

Intervention Type DRUG

Placebo

Standard care

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Standard care

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Age 60 years old and above
2. Provided consent for the study
3. Patients with solitary hip fracture (no other fracture) - intracapsular neck of femur fracture, intertrochanteric fracture
4. Either awaiting hip fracture surgery or no plans for hip fracture surgery within the next 24 hours

Exclusion Criteria

1. Patients with cognitive impairment or inability to give consent, or refusal to give consent
2. Multiple fracture cases
3. Peri-prosthetic fractures and revisions
4. Subclinical vertebral fractures
5. Hip fractures due to major accidents such as road traffic accidents, fall from height or more than 2 meters
6. Multiple trauma
7. Pathological fractures secondary to metastases
8. Patients with contraindications to block performance

* Coagulopathy as demonstrated by PT/PTT/INR
* On antiplatelets or anticoagulation
* Infection/ compromised skin integrity at site of block performance
* Allergy to local anaesthetics and opioids

Minimum Eligible Age

60 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No