Caries Inhibitory Effect of Nano Silver and Tri Calcium Phosphate Varnishes Among Visually Impaired Children

NCT ID: NCT06576960

Last Updated: 2024-08-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-10-11

Study Completion Date

2023-04-13

Brief Summary

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Assessment of pH,streptococcus mutants count, lactobacillus count and immunoglobulin A among visually impaired children after nano silver varnish application it tri calcium phosphate phosphate varnish application

Detailed Description

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Sixty children will be randomly divided into three equal treatment groups, composed of 20 children each, according to the type of material used as follows:

* Group I: children will receive oral health education and nano silver fluoride varnish.
* Group II: children will receive oral health education and tri calcium phosphate varnish.
* Group III: children will receive oral health education

for all children ,Assessment of pH, streptococcus mutants count, lactobacillus count and immunoglobulin A will be assessed at baseline, one day , 3 months and 6 months after application

Conditions

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Dental Caries

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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nano silver varnish

new fluoride varnish

Group Type EXPERIMENTAL

Nano silver fluoride varnish and tri calcium phosphate varnish

Intervention Type DRUG

Fluoride varnishes

tri calcium phosphate varnish

fluoride varnish contain calcium phosphate

Group Type EXPERIMENTAL

Nano silver fluoride varnish and tri calcium phosphate varnish

Intervention Type DRUG

Fluoride varnishes

health education

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Nano silver fluoride varnish and tri calcium phosphate varnish

Fluoride varnishes

Intervention Type DRUG

Other Intervention Names

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health education

Eligibility Criteria

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Inclusion Criteria

Visually impaired children

Exclusion Criteria

* uncooperative children or children not willing to participate in the study.
* Children with systemic diseases
* Children with bronchial asthma.
* Children who were on antibiotic or medications that might affect oral flora or salivary flow taken within the previous 3 months
* History of fluoride treatment in the past 3-4 weeks.
Minimum Eligible Age

8 Years

Maximum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tanta University

OTHER

Sponsor Role collaborator

Hadeer Mohammed Abd El wahab

OTHER

Sponsor Role lead

Responsible Party

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Hadeer Mohammed Abd El wahab

El Mahalla Elkobra

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Hatem Amin, PhD

Role: STUDY_DIRECTOR

Faculty of dentistry . Tanta university

Locations

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Faculty of dentistry

Tanta, Tanta City, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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OH12-12

Identifier Type: -

Identifier Source: org_study_id

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