The Immediate Effect of Combined Terminal Knee Extension Exercise With Audible Cues

NCT ID: NCT06565325

Last Updated: 2025-07-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-02-10

Study Completion Date

2025-03-07

Brief Summary

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Typically, patients perform TKE by themselves after exercise prescription. The investigators thought that a lack of attention and preferred speed of patients might not provide the best outcome. Therefore, an increased effectiveness of TKE is interesting for physical therapy implication. Besides, adding sensory input which is audible cues or rhythm during exercise may enhance the efficacy of the exercise by increasing neuromuscular control and function.

Therefore, the study aimed to investigate the immediate effects of combined TKE with audible cues on motor unit behavior. The researchers expect that adding rhythm from the metronome will enhance neuromuscular control which may change motor unit behavior of VM muscle. The findings of the study may have helped explain the mechanism behind the acute effects of combined TKE with audible cues on VM function and their potential application in the field of physical therapy.

This study aims to investigate the immediate effect of combined TKE with audible cues on motor unit behavior in healthy participants and to investigate reliability of decomposition electromyography procedure during single leg squat.

Detailed Description

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A metronome will be used to provide rhythmic exercise. Participants will stand with their feet in line with their shoulders as starting position and straping at the knee. Exercise intensity is 60% of the 1RM weight. At the beginning of the exercise, participants will be asked to bend their knees following the pull of the resistance and exert force to straighten the knee (10 times/set and 3 sets). 180 seconds of resting will be allowed between sets.

Conditions

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Muscle Weakness

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

There are 2 groups in the current study including exercise with and without audible cues.
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
Participant group

Study Groups

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Experimental group

Terminal Knee Extension Exercise with Audible Cues

Group Type EXPERIMENTAL

Exercise + Audible Cues

Intervention Type BEHAVIORAL

Combined Terminal Knee Extension Exercise with Audible Cues

Control group

Terminal Knee Extension Exercise without Audible Cues

Group Type ACTIVE_COMPARATOR

Exercise

Intervention Type BEHAVIORAL

Terminal Knee Extension Exercise

Interventions

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Exercise + Audible Cues

Combined Terminal Knee Extension Exercise with Audible Cues

Intervention Type BEHAVIORAL

Exercise

Terminal Knee Extension Exercise

Intervention Type BEHAVIORAL

Other Intervention Names

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Metronome

Eligibility Criteria

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Inclusion Criteria

* Aged range between 18 and 30 years
* BMI of 18.5-25 kg/m2
* Male or female
* Lightly active or sedentary {Physical activity level (PAL= 1.4-1.69)}

Exclusion Criteria

* History of serious injury or operation of lower back and lower extremities such as fracture
* Musculoskeletal problems of lower back and lower extremities in 6 months before the study
* Single-leg stance test \< 43 seconds (26). and range of weight-bearing lunge test \< 9.1 cm
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mahidol University

OTHER

Sponsor Role lead

Responsible Party

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Komsak Sinsurin

Asst.Prof.Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Faculty of Physical Therapy, Mahidol University

Nakhon Pathom, Salaya, Thailand

Site Status

Countries

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Thailand

Other Identifiers

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MU-CIRB 2024/021.0802

Identifier Type: -

Identifier Source: org_study_id

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