Exercise With Audible Cues on Motor Unit Behavior in Athletes With Anterior Cruciate Ligament Reconstruction

NCT ID: NCT06662955

Last Updated: 2025-12-12

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 40 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-10-20
• Study Completion Date: 2026-12-30

Brief Summary

The closed kinetic chain (CKC) of terminal knee extension exercise (TKE) is designed to activate VM activity for knee injury training. This CKC exercise is effective for highest recruiting muscle activity, especially safe for post-operative knee surgery. The study of ACL reconstruction rehabilitation guideline suggests that exercises can be applied within the early phase of rehabilitation to prevent knee laxity and less knee pain compared to open chain exercise. Therefore, it is interesting to investigate the effects of TKE exercise synchronized with metronome pace on change of VM motor unit behavior in post operative ACL reconstruction. This study focuses on the immediate effect of 1-seesion TKE and expects that adding metronome during TKE will enhance neuromuscular control of VM and may change motor unit behavior.

Detailed Description

This study investigates the effect of exercise with sensory integration technique on neuromuscular control in athletes with anterior cruciate ligament reconstruction.

Conditions

Therapeutic Exercise; Physical Therapy Techniques; Neuromuscular Function

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Exercise without audible cues

Terminal knee extension exercise without audible cues

Group Type: ACTIVE_COMPARATOR

Exercise

Intervention Type: BEHAVIORAL

Terminal knee extension exercise

Exercise with audible cues

Terminal knee extension exercise with audible cues

Group Type: EXPERIMENTAL

audible cues

Intervention Type: BEHAVIORAL

Terminal knee extension exercise with audible cues

Interventions

audible cues

Terminal knee extension exercise with audible cues

Intervention Type: BEHAVIORAL

Exercise

Terminal knee extension exercise

Intervention Type: BEHAVIORAL

Other Intervention Names

Exercise with audible cues

Eligibility Criteria

Inclusion Criteria

• Male or female participants who receive primary ACL reconstruction within 2 weeks with or without meniscus repair
• No or mild resting pain (Numeric rating scale ≤ 3)
• Reconstruction procedures using autograft including hamstrings or bone-patella bone grafts
• Age range 18-35 years (33).
• BMI of 18.5-25 kg/m² (34).
• Tegner activity scale ≥ level 4

Exclusion Criteria

• Non-weight bearing within 2 weeks after the operation (prescription from surgeon)
• Hearing problem, such as being unable to hear the metronome sound or being unable to synchronize exercises with the metronome correctly
• Limitations in knee extension range caused by joint stiffness evaluated by using passive knee range of motion
• Unable to perform active and passive ≥ 30º knee flexion on the operative side
• History of serious injury or operation of lower back and lower extremities such as fracture
• Lower back or lower extremities pain within 6 months before the study
• On the pain killer medication

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 35 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Mahidol University

OTHER

Sponsor Role: lead

Responsible Party

Komsak Sinsurin

Asst.Prof.Dr.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Faculty of Physical Therapy, Mahidol University

Salaya, Changwat Nakhon Pathom, Thailand

Site Status: RECRUITING

Countries

Thailand

Central Contacts

Komsak Sinsurin, PT, Ph.D., DPT

Role: CONTACT

komsak.sin@mahidol.edu

6855547313

Sakda Nitkotom, B.Sc.

Role: CONTACT

Sakda.nit@hotmail.com

0869853212

Facility Contacts

Wanida Sawangnat, M.Sc.

Role: primary

wanida.swa@mahidol.ac.th

+66 24415450 ext. 20220

Other Identifiers

MU-CIRB 2024/242.3009

Identifier Type: -

Identifier Source: org_study_id