Oral (Hypo-)Function, General Function and Nutritional Status in Elderly Hospitalized Patients

NCT ID: NCT06557226

Last Updated: 2025-03-30

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 61 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2020-09-12
• Study Completion Date: 2023-09-10

Brief Summary

The goal of this observational study is to learn about the effects of a reduced oral function on the nutritional status of non-acute hospitalized elders and on their oral health quality of life.

Detailed Description

Malnutrition is highly prevalent among the elderly, many authors reported on the relationship between oral health and nutrition. However the the relationship between the dental state and the nutritional status was always limited to anatomical criteria such as number of teeth and the presence of prosthetic reconstructions.

The oral function is classified into 4 stages healthy state, oral frailty, oral hypofunction and oral dysfunction. The classification into the different stages result from an examination of 7 parameters: the oral hygiene, the oral dryness, the occlusal force, the tongue-lip motor function, the tongue pressure, the chewing function and the swallowing function.

This study aims to correlate the oral function with the nutritional status of non-acute hospitalized elders. And to further investigate the correlation between the different parameters defining the oral function and the oral health related quality of life (OHRQoL) as measured by theGeneral Oral Health Assessment Index.

A total 60 participants will be recruited in the University Hospital of Geneva, Loëx rehabilitation center. The investigators will see the patient for 2 visits after informed consent. The first visit will be 45 minutes long and will include a dental examination and an examination of the oral hygiene, the oral dryness, the tongue lip motor function, the tongue pressure, the occlusal force and the swallowing function. Diagnosis for nutrition according to the Glim criteria will be done. Furthermore, the participants will be asked to fill an oral health quality of life questionnaire comprising 12 questions.

Oral hypo function will be defined as a state when 3 or more signs were present from the 7 parameters examined.

Linear multiple regression analysis is used to examine the relationship between the nutritional status and oral function. Spearman's rank correlation coefficient will be used to correlate the oral function score and oral health related quality of life.

Conditions

Oral Health; Oral Health Related Quality of Life; Nutrition Disorders in Old Age

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

patient with oral hypofunction with 3 impaired oral functional parameters

patient's will receive an oral examination comprising the evaluation of 7 parameters: the oral hygiene, the oral dryness, the occlusal force, the tongue-lip motor function, the tongue pressure, the chewing function and the swallowing function. Oral hypofunction is defined as a state when 3 or more signs were present.

oral and nutritional examination

Intervention Type: OTHER

Participants will receive a comprehensive oral examination, nutritional examination and will fill an oral health related quality of life questionnaire.

Interventions

oral and nutritional examination

Participants will receive a comprehensive oral examination, nutritional examination and will fill an oral health related quality of life questionnaire.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• • Aged 70 years or over

• Hospitalized in Geneva University Hospitals, in rehabilitation or in long term care (Loëx)
• Able to follow simple instructions and perform the tests
• Understand French and complete or answer the questionnaire
• Give written informed consent
• Consent can be obtained from their next of kin or legal representative if necessary
• Have been admitted into the hospital no longer 15 days before inclusion

Exclusion Criteria

• Patients with tube/intravenous feeding
• Poorly-controlled diabetes (Liu et al., 2015)
• Patients with gastro-intestinal diseases or symptoms (nausea, vomiting, diarrhea, constipation) affecting oral intake
• If the patient is taking an antimicrobial treatment at this time.

• Minimum Eligible Age: 70 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Geneva, Switzerland

OTHER

Sponsor Role: lead

Responsible Party

Frauke Müller

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Christophe Graf, Pr.

Role: STUDY_DIRECTOR

University Hospital, Geneva

Locations

University clinics of dental medicine

Geneva, Canton of Geneva, Switzerland

Geneva University Hospital

Geneva, Canton of Geneva, Switzerland

Countries

Switzerland

Other Identifiers

2019-01338

Identifier Type: -

Identifier Source: org_study_id