Targeting the Skeletal Muscle to Treat Metabolic Dysfunction-associated Steatotic Liver Disease
NCT ID: NCT06506513
Last Updated: 2024-07-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
60 participants
INTERVENTIONAL
2024-10-31
2026-09-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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control group
in this control group, patients will perform non-cardiovascular non-intensity training (stretching, meditation).
Low intensity exercise training
Low intensity exercise training
moderate-intensity low interval training group
In this group, patients will perform moderate-intensity low interval training.
Moderate intensity exercise training
Moderate intensity exercise training
high-intensity interval training
In this group, patients willp erform high-intensity interval training.
High-intensity interval training
High-intensity interval training
Interventions
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High-intensity interval training
High-intensity interval training
Moderate intensity exercise training
Moderate intensity exercise training
Low intensity exercise training
Low intensity exercise training
Eligibility Criteria
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Inclusion Criteria
* confirmed excessive muscle lipid content at imaging
* stable weight
Exclusion Criteria
* contraindications to physical activity
* excessive alcohol consumption
18 Years
70 Years
ALL
Yes
Sponsors
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Concerted Research Action
UNKNOWN
Fonds National de la Recherche Scientifique
OTHER
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
OTHER
Responsible Party
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Principal Investigators
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Nicolas Lanthier, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Locations
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Cliniques universitaires Saint-Luc
Brussels, , Belgium
Centre d'investigation clinique en nutrition
Louvain-la-Neuve, , Belgium
Countries
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Central Contacts
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Facility Contacts
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Guillaume Henin, MD, PhD student
Role: primary
References
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Henin G, Loumaye A, Leclercq IA, Lanthier N. Myosteatosis: Diagnosis, pathophysiology and consequences in metabolic dysfunction-associated steatotic liver disease. JHEP Rep. 2023 Nov 14;6(2):100963. doi: 10.1016/j.jhepr.2023.100963. eCollection 2024 Feb.
Henin G, Loumaye A, Deldicque L, Leclercq IA, Lanthier N. Unlocking liver health: Can tackling myosteatosis spark remission in metabolic dysfunction-associated steatotic liver disease? Liver Int. 2024 Aug;44(8):1781-1796. doi: 10.1111/liv.15938. Epub 2024 Apr 16.
Other Identifiers
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ST-IR-01 MYO-MASLD
Identifier Type: -
Identifier Source: org_study_id
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