Treprostinil in Newborns With Pulmonary Hypertension; a Non-Interventional Study to Collect Data on Drug Utilization, Safety, and Effectiveness

NCT ID: NCT06499363

Last Updated: 2025-09-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-02-25

Study Completion Date

2027-12-31

Brief Summary

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This observational study will seek to describe the uses and safety and efficacy outcomes of treprostinil in clinical practice in patients with persistent pulmonary hypertension (PPHN).

Detailed Description

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Conditions

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Persistent Pulmonary Hypertension of Newborn

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Eligibility Criteria

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Inclusion Criteria

1. Newborn infants who received at least one dose of IV or SC treprostinil as per clinical practice within 5 years from the moment of data collection.
2. Aged up to 44 weeks after conception at treprostinil initiation.
3. Pulmonary hypertension (PH) or suspicion of PH at the moment of treprostinil initiation.
4. Parent(s) or legally authorized representative(s) provides non-opposition consent for the patient participation in the study.
5. Newborn infants affiliated to French social security.

Exclusion Criteria

* None.
Maximum Eligible Age

44 Weeks

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ferrer Internacional S.A.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU Lyon (HCL) - Hopital Femme Mère Enfant

Bron, , France

Site Status RECRUITING

Réanimation néonatale CHU Grenoble Alpes - Hôpital Couple Enfant

Grenoble, , France

Site Status RECRUITING

CHU Lille - Clinique de Néonatalogie

Lille, , France

Site Status RECRUITING

CHU de Toulouse Hopital des enfants - Réanimation Néonatale

Toulouse, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Ferrer MedInfo

Role: CONTACT

609850565

Facility Contacts

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Marine Butin, Medical Doctor

Role: primary

+33 (0)4 27 85 52 84

Amélie Desrumaux, Medical Doctor

Role: primary

+33(0)4 76 76 55 03

Kevin Leduc, Medical Doctor

Role: primary

+33 03 20 44 58 89

Sophie Breinig, Medical Doctor

Role: primary

+33 (0)5 34 55 84 77

Other Identifiers

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FREM-NIS-2301

Identifier Type: -

Identifier Source: org_study_id

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