Pulmonary Vascular Disease and Cardiac Performance in Extreme Preterm Infants
NCT ID: NCT04114435
Last Updated: 2025-06-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
RECRUITING
150 participants
OBSERVATIONAL
2019-10-12
2025-12-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Exercise Intervention to Rescue the Adverse Effect of Preterm Birth on Cardiovascular and Pulmonary Health.
NCT03504215
Novel Echocardiographic Methods for Early Identification of Neonates at Risk for Chronic Pulmonary Hypertension
NCT04402645
Pulmonary Hypertension in Extremely Preterm Infants
NCT05136235
Conditions of Realization of the Echocardiography in Newborns
NCT02893956
Prematurity-Related Ventilatory Control
NCT03464396
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
The principal investigator also hypothesize that premature newborns with poor cardiac performance and/or pulmonary hypertension have higher morbidities and poorer neuro-developmental outcomes.
The principal investigator also hypothesize that premature newborns with poor cardiac performance and/or pulmonary hypertension have higher morbidities and poorer neuro-developmental outcomes and that novel echocardiography techniques will detect anomalies not uncovered by conventional imaging, and that early echocardiography may identify those with later pulmonary hypertension.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
COHORT
PROSPECTIVE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Neonatal profile
Echocardiography at:
* 7 to 10 days of chronological age
* 35 to 37 weeks post-menstrual age (PMA = corrected age);
* 39 to 44 weeks PMA; Term equivalent
Echocardiography
Diagnostic test which uses ultrasound waves to make images of the heart chambers, valves and surrounding structures
Infant profile ( between 4 months and 9 months)
* Echocardiography
* Ages \& stages questionnaires CAT/CLAMS assessment
Echocardiography
Diagnostic test which uses ultrasound waves to make images of the heart chambers, valves and surrounding structures
Pediatric profile (36 months and 5 years)
* Echocardiography
* Ages \& stages questionnaires CAT/CLAMS assessment
* Results from 18 months PMA Bayley will be retrieved Figure 1: Premature population - Groups Recruited simultaneously
Echocardiography
Diagnostic test which uses ultrasound waves to make images of the heart chambers, valves and surrounding structures
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Echocardiography
Diagnostic test which uses ultrasound waves to make images of the heart chambers, valves and surrounding structures
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* All infants born at \<29 weeks' gestational age followed at MCH clinic after an admission in the NICU for prematurity \<29 weeks
Exclusion Criteria
* Congenital severe lung or airway malformation (choanal atresia, trachea-esophageal fistula or congenital pulmonary airway malformation)
* Genetic disorder (Trisomy 21).
7 Days
5 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
McGill University Health Centre/Research Institute of the McGill University Health Centre
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Gabriel Altit
Neonatologist
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Mcgill University Health Centre
Montreal, Quebec, Canada
Countries
Review the countries where the study has at least one active or historical site.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
2020-5893
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.