Advanced Technology-based Rehabilitation Post-stroke Gait Re-learning

NCT ID: NCT06497309

Last Updated: 2024-07-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-01-26

Study Completion Date

2026-06-01

Brief Summary

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High-tech therapy, an innovative field of neurorehabilitation, has expanded rapidly in recent years. Advances in technology have enabled the use of devices that can assist with movement development from simple movements to more complex tasks.

This research investigates the effectiveness of rehabilitation programmes that complement robot-assisted therapy to help people relearn to walk in post-stroke rehabilitation. This would be measured in two variations, with the patient (in addition to a complex rehabilitation programme of conventional physiotherapy, occupational therapy, hydrotherapy, etc.) receiving either treadmill or no treadmill treatment. In both cases, the therapies will be carried out with advanced technology-based equipment (both treatments are part of the daily routine of the Institute's treatments, and the equipment will be used according to the instructions in the user manual), the C-Mill interactive robot-assisted device will be used for treadmill therapy, and the Andago robot-assisted device for non- treadmill therapy. There is no sharp distinction between the two systems. The inclusion and exclusion criteria are set so patients' conditions meet the indications for both devices, and patients eligible for treatment with one device are included in the other.

In our study, 80 patients will be selected.

Detailed Description

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The main objective of this research is to investigate the effectiveness of rehabilitation programmes in post-stroke rehabilitation using advanced technology-based therapy to assist in relearning walking. This will be measured in two variations: the patient will be randomly assigned (in addition to a complex rehabilitation programme of traditional physiotherapy, occupational therapy, hydrotherapy, etc.) to receive either treadmill treatment or no treadmill treatment. In both cases, the therapies are carried out using advanced technological equipment.

The investigators will enrol 80 people in our study. The comparison will be between 40 and 40 people, the main groups differing in terms of the type of advanced technology device used in the rehabilitation programme and whether they received treadmill or non-treadmill treatment. In total, they will participate in 20 sessions of therapy.

Furthermore, the investigators observe whether a greater change in condition can be measured in the early post-stroke period (0-3 months) or the late period (3 months-1 year) in specific parameters of the patient's gait. The time since the stroke provides an opportunity for subgroup analysis, but the number of cases limits this. This is significant because it is still an open question in the international literature regarding advanced technology-based therapy.

In all cases, the examination starts and ends with the DIERS motion analysis system, a light-optical scanning method based on VRS (Video Raster Stereography) and a sensor-equipped treadmill that allows the measurement of several parameters of gait and balancing ability. In addition, traditional physiotherapy assessment methods (Timed Up and Go, Berg Balance Test, 6-minute gait test, 10-metre gait test, Functional Independence Measure, Barthel) are used to assess gait pattern and self-sufficiency.

Conditions

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Stroke Gait Disorders, Neurologic

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Treadmill group

In both groups, using advanced technology-based tools (both treatments are part of the daily routine of the Institute's treatments and are used according to the instructions in the user manual), for the treadmill therapy, we use the C-Mill interactive high-tech device.

Treadmill training

Intervention Type DEVICE

Therapy with treadmill-based advanced technology device.

DIERS

Intervention Type DEVICE

The examination starts and ends with the DIERS motion analysis system, a light-optical scanning method based on VRS (Video Raster Stereography) and a sensor-equipped treadmill that allows the measurement of several parameters of gait and balancing ability.

Traditional physiotherapy assessments

Intervention Type OTHER

Traditional physiotherapy assessment methods (Timed Up and Go, Berg Balance Test, 6-minute gait test, 10-metre gait test, Functional Independence Measure, Barthel) are used to assess gait pattern and self-sufficiency.

Overground group

In both groups, we use an advanced technology-based device (both treatments are part of the daily routine of the Institute's treatments and are used according to the instructions in the user manual), and the Andago high-tech device for non-runner therapy.

Overground training

Intervention Type DEVICE

Therapy using an advanced technological device enables exercise on the ground.

DIERS

Intervention Type DEVICE

The examination starts and ends with the DIERS motion analysis system, a light-optical scanning method based on VRS (Video Raster Stereography) and a sensor-equipped treadmill that allows the measurement of several parameters of gait and balancing ability.

Traditional physiotherapy assessments

Intervention Type OTHER

Traditional physiotherapy assessment methods (Timed Up and Go, Berg Balance Test, 6-minute gait test, 10-metre gait test, Functional Independence Measure, Barthel) are used to assess gait pattern and self-sufficiency.

Interventions

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Treadmill training

Therapy with treadmill-based advanced technology device.

Intervention Type DEVICE

Overground training

Therapy using an advanced technological device enables exercise on the ground.

Intervention Type DEVICE

DIERS

The examination starts and ends with the DIERS motion analysis system, a light-optical scanning method based on VRS (Video Raster Stereography) and a sensor-equipped treadmill that allows the measurement of several parameters of gait and balancing ability.

Intervention Type DEVICE

Traditional physiotherapy assessments

Traditional physiotherapy assessment methods (Timed Up and Go, Berg Balance Test, 6-minute gait test, 10-metre gait test, Functional Independence Measure, Barthel) are used to assess gait pattern and self-sufficiency.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Hemiparetic patient who has had a stroke;
* ischaemic or haemorrhagic stroke confirmed by CT or MRI;
* female or male between 40 and 75 years of age;
* subgroup 1: less than 3 months since stroke,
* subgroup 2: more than 3 months but less than 1 year since stroke;
* physical fitness adequate for the exertion of the treatment;
* right or left lower limb involvement;
* score 3 on the Functional Ambulation Categories (FAC) scale, i.e. Indicates a patient who can ambulate on a level surface without manual contact of another person but requires standby guarding of one person either for safety or verbal cueing;
* or score 4 on the Functional Ambulation Categories (FAC) scale, i.e. Indicates a patient who can ambulate independently on a level surface but requires supervision to negotiate (e.g. stairs, inclines, non-flat surfaces);
* be able to participate in therapy and cooperate based on cognitive function;
* signed informed consent.

Exclusion Criteria

* More than 1 year has passed since the stroke;
* scores less than or equal to 3 on the Functional Ambulation Categories (FAC) scale;
* patients who were unable to walk independently before the stroke;
* patients treated with botulinum toxin in the lower limb in the last 3 months;
* use of other lower limb advanced technology treatments during the study;
* a person with limited capacity;
* not physically able to bear weight;
* severe aphasia (impairment of understanding or expression that severely impedes communication);
* other condition that precludes the use of C-Mill or Andago:

* severe emotional disturbance;
* mentally incapacitated patient;
* severe contracture or spasticity preventing the patient from being placed in the machine;
* pregnancy;
* skin disease in the area of contact with the straps;
* fever;
* unhealed fracture fracture;
* inability to use the device due to weight and height limitations of the device;
* epilepsy if you have had a seizure within a year;
* severe visual impairment.
Minimum Eligible Age

40 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Semmelweis University

OTHER

Sponsor Role collaborator

National Institute for Medical Rehabilitation, Hungary

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Gábor Fazekas, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

National Institute for Medical Rehabilitation, Hungary

Locations

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National Institute for Medical Rehabilitation

Budapest, Pest County, Hungary

Site Status

Countries

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Hungary

Other Identifiers

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OMINT-58-1/2023

Identifier Type: -

Identifier Source: org_study_id

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