A Study of Clinical Characteristics ,Risk Factors and Outcome of Lupus Nephritis Among Children With Systemic Lupus Erthromatousus in Sohag Univeristy Hospital

NCT ID: NCT06491602

Last Updated: 2024-07-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-06-24

Study Completion Date

2025-06-24

Brief Summary

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systemic lupus erthrematosus is an inflamatory and autoimmune condition characterized by multisystem affection and chronic course with unpredictable flares despite potentially afffecting every oragan . kidney involvment are the most common

Detailed Description

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Conditions

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Lupus Nephritis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Interventions

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renal biobsy

analsis of renal biobsy and decide grade of renal affection

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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abdomial us laboratory investigation for lupus nephritis

Eligibility Criteria

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Inclusion Criteria

\- aim to include all children fulfilling diagnostic criteria

Exclusion Criteria

* children with other rheumatological disorder neonates chidren with other nephrolgy disorder
Minimum Eligible Age

1 Month

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sohag University

OTHER

Sponsor Role lead

Responsible Party

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Randa Abdelgawad Hussien

Resident-pediatric department-sohag hospital university

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Sohag university Hospital

Sohag, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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randa A ali, resident

Role: CONTACT

01100128936

dr monser M Mohammed, assistant professor

Role: CONTACT

01026372799

Facility Contacts

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Magdy M Amin, professor

Role: primary

References

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Tsokos GC. Systemic lupus erythematosus. N Engl J Med. 2011 Dec 1;365(22):2110-21. doi: 10.1056/NEJMra1100359. No abstract available.

Reference Type BACKGROUND
PMID: 22129255 (View on PubMed)

Hiraki LT, Feldman CH, Liu J, Alarcon GS, Fischer MA, Winkelmayer WC, Costenbader KH. Prevalence, incidence, and demographics of systemic lupus erythematosus and lupus nephritis from 2000 to 2004 among children in the US Medicaid beneficiary population. Arthritis Rheum. 2012 Aug;64(8):2669-76. doi: 10.1002/art.34472.

Reference Type BACKGROUND
PMID: 22847366 (View on PubMed)

Demir S, Gulhan B, Ozen S, Celegen K, Batu ED, Tas N, Orhan D, Bilginer Y, Duzova A, Ozaltin F, Topaloglu R. Long-term renal survival of paediatric patients with lupus nephritis. Nephrol Dial Transplant. 2022 May 25;37(6):1069-1077. doi: 10.1093/ndt/gfab152.

Reference Type BACKGROUND
PMID: 33826705 (View on PubMed)

Hiraki LT, Benseler SM, Tyrrell PN, Hebert D, Harvey E, Silverman ED. Clinical and laboratory characteristics and long-term outcome of pediatric systemic lupus erythematosus: a longitudinal study. J Pediatr. 2008 Apr;152(4):550-6. doi: 10.1016/j.jpeds.2007.09.019. Epub 2007 Nov 5.

Reference Type BACKGROUND
PMID: 18346514 (View on PubMed)

Other Identifiers

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Soh-Med-24-06-22MS

Identifier Type: -

Identifier Source: org_study_id

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