Bionenergetic Balance During CVVH

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-02-01

Study Completion Date

2024-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The bioenergetic balance is the sum of energy exchanged during CRRT and is mostly defined by citrate glucose and lactate. When CRRT was performed with the older dialysis fluids, glucose and lactate could be an important source of energy next to citrate when used as predilution (6, 7). During continuous venovenous hemofiltration (CVVH), a subgroup of CRRT which is performed with the newer dialysis fluids without lactate or glucose as advocated by the KDIGOguidelines, glucose and in a minor way lactate mostly induce a loss of energy. The first aim is to determine how this bioenergetic balance impacts energy need compared to the measured energy with indirect calorimetry and how nutrition therapy needs to be adapted.

Also, disease specific predicting equation have been created for patients suffering from acute kidney injury treated with renal replacement therapy. How this predicting equation and other existing predicting equations agree with the measured REE has not been validated yet. The second aim is to determine how predictive equations correlate with measured REE in patients treated with CVVH.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Intra Dialytic Parenteral Nutrition and Nutritional Gap Nutritional Gap Identified by Indirect Calorimetry

NCT05568914

Chronic Kidney Diseases Protein Energy Wasting

RECRUITING NA

Simulation for Continuous Veno-venous Hemofiltration in Intensive caRe

NCT02379234

Hemofiltration Nurse Training Health Care Provider Education

COMPLETED NA

Macrohemodynamic Impact of Fluid Removal With Net Ultrafiltration in Patients With Continuous Renal Replacement Therapy

NCT06425289

Fluid Removal Critically Ill Continuous Renal Replacement Therapy +1 more

NOT_YET_RECRUITING

Effects of Continuous Venous Dialysis and Hemodialysis on Fluid Dynamics by Bioreactance Method

NCT03905122

Renal Dialysis

COMPLETED

Novel Equation for Estimating Resting Energy Expenditure in Dialysis Patients

NCT04947839

Resting Energy Expenditure Peritoneal Dialysis Equation

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Acute Kidney Injury Continuous Venovenous Hemofiltration Energy Metabolism Resting Energy Expenditure Nutrition Therapy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Group 1

all patients

bioenergetic balance

Intervention Type OTHER

Bioenergetic balance is calculated for all patients who had a resting energy expenditure measurement with indirect calorimetry.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

bioenergetic balance

Bioenergetic balance is calculated for all patients who had a resting energy expenditure measurement with indirect calorimetry.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients admitted to the adult ICU (01/01/2021-30/09/2022)
* At least one indirect calorimetry measurement (ventilator) or calculation based on harris benedict OR 25Kcal/kg/day
* Combined with bio energetic balance measurement
* Receiving CVVH during intensive care stay

Exclusion Criteria

* Patients admitted outside of the inclusion period will be excluded
* The absence of an indirect calorimetry measurement (ventilator) or calculation - based on the Harris Benedict OR 25Kcal/kg/day formula OR The absence of a bio energetic balance measurement
* The absence of CVVH during intensive care stay
* Pediatric (intensive care unit) patients

Minimum Eligible Age

18 Years

Maximum Eligible Age

130 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No