Glymphatic MRI Study

NCT ID: NCT06452459

Last Updated: 2024-06-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

10 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-07-01

Study Completion Date

2028-07-01

Brief Summary

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This study aims at identifying neuroimaging markers of glymphatic function in humans.

Detailed Description

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Conditions

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Sleep Deprivation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Interventions

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No interventinon

No intervention is anticipated. This is an observational study.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Ability to undergo MRI without anesthesia
* Calculated GFR greater or equal to 60 mL/min/1.73 m2

Exclusion Criteria

* Inability to obtain consent
* Subject is incarcerated, pregnant, or lactating or suspects they may be pregnant
* Known allergic or hypersensitivity reactions to gadolinium
* Three or more drug allergies from separate drug classes
* Recent or expected beed for imaging with iodinated contrast
* Contraindications to MRI: claustrophobia, weight greater than maximum MRI scanner capacity, presence of metallic foreign body, or implanted devices not documented as MRI safe
* History of neurosurgical procedure or cervical surgery
* Current use of anticoagulation medications
* Contraindication to lumbar puncture (creatinine or INR elevated above laboratory standard cutoffs)
Minimum Eligible Age

18 Years

Maximum Eligible Age

89 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Oregon Health and Science University

OTHER

Sponsor Role lead

Responsible Party

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Juan Piantino

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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IT Gadolinium Study

Identifier Type: -

Identifier Source: org_study_id

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