Postoperative BMI Changes and Functional Outcomes in Knee and Hip Arthroplasty

NCT ID: NCT06440863

Last Updated: 2024-06-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

459 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-01-01

Study Completion Date

2024-05-01

Brief Summary

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PURPOSE Obesity poses challenges to preoperative mobility and functional recovery for arthroplasty patients, yet postoperative weight loss remains elusive. This study aims to investigate postoperative weight changes and their impact on functional scores following knee and hip arthroplasty, exploring factors influencing these changes.

METHODS A total of 459 knee and hip arthroplasty cases with a 2-year follow-up were analyzed. BMI and Oxford scores were tracked, alongside factors including comorbidities, corticosteroid use, physiotherapy, and unilateral vs. bilateral surgery.

EXPECTED OUTCOMES Based on the study's design and the data available, we anticipate observing the impact of changes in patients' BMI on clinical scores as an independent variable. Additionally, we aim to elucidate the effects of comorbidities, corticosteroid use, physiatrist follow-up, and the type of surgical procedure on both BMI and clinical outcomes. Through this analysis, we expect to gain a comprehensive understanding of how these factors interplay to influence postoperative recovery and overall patient health.

Detailed Description

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Conditions

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Arthropathy Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Total Knee Arthroplasty

Patients indicated for total knee arthroplasty.

Group Type ACTIVE_COMPARATOR

Total Knee Arthroplasty

Intervention Type PROCEDURE

Patients undergoing total knee arthroplasty

Total Hip Arthroplasty

Patients indicated for total hip arthroplasty.

Group Type ACTIVE_COMPARATOR

Total Hip arthroplasty

Intervention Type PROCEDURE

Patients undergoing total hip arthroplasty

Interventions

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Total Knee Arthroplasty

Patients undergoing total knee arthroplasty

Intervention Type PROCEDURE

Total Hip arthroplasty

Patients undergoing total hip arthroplasty

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients who underwent primary TKA and THA with a 2-year follow-up were included

Exclusion Criteria

* Patients who underwent bariatric surgery before or after the surgery
* Incomplete 2-year follow-up
* Whom BMI or Oxford scores could not be accessed
Minimum Eligible Age

20 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Istanbul University - Cerrahpasa

OTHER

Sponsor Role lead

Responsible Party

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Mete Ozer

Research Assistant

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Cumhur Deniz Davulcu

Role: PRINCIPAL_INVESTIGATOR

Istanbul University - Cerrahpasa

Locations

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Istanbul University - Cerrahpasa, Cerrahpasa Faculty of Medicine

Istanbul, Fatih, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Woodruff MJ, Stone MH. Comparison of weight changes after total hip or knee arthroplasty. J Arthroplasty. 2001 Jan;16(1):22-4. doi: 10.1054/arth.2001.9826.

Reference Type BACKGROUND
PMID: 11172266 (View on PubMed)

Riddle DL, Singh JA, Harmsen WS, Schleck CD, Lewallen DG. Clinically important body weight gain following knee arthroplasty: a five-year comparative cohort study. Arthritis Care Res (Hoboken). 2013 May;65(5):669-77. doi: 10.1002/acr.21880.

Reference Type BACKGROUND
PMID: 23203539 (View on PubMed)

Inacio MC, Silverstein DK, Raman R, Macera CA, Nichols JF, Shaffer RA, Fithian D. Weight patterns before and after total joint arthroplasty and characteristics associated with weight change. Perm J. 2014 Winter;18(1):25-31. doi: 10.7812/TPP/13-082.

Reference Type BACKGROUND
PMID: 24626069 (View on PubMed)

Other Identifiers

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Y7MQG7gO

Identifier Type: -

Identifier Source: org_study_id

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