Parkinsonism-Related Oscillations in the Cortico-Basal Ganglia-Thalamic Network During Movement: Beyond the Frequency Range
NCT ID: NCT06438419
Last Updated: 2025-05-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
20 participants
INTERVENTIONAL
2025-04-16
2027-04-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
BASIC_SCIENCE
NONE
Study Groups
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Recruited patient
Patient with idiopathic Parkinson's disease and having a STN DBS with a PERCEPT™ for less than a year or being candidate for subthalamic nucleus deep brain stimulation with the PERCEPT™ device (first-implantation)
Electrophysiological recordings
Electrophysiological recordings will be made during a motor task in four different conditions:
1. without pharmacological treatment and without stimulation (Off condition),
2. without pharmacological treatment and during stimulation (DBS condition),
3. during pharmacological treatment and without stimulation (DOPA condition),
4. during pharmacological treatment and stimulation (DOPA+DBS condition).
Interventions
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Electrophysiological recordings
Electrophysiological recordings will be made during a motor task in four different conditions:
1. without pharmacological treatment and without stimulation (Off condition),
2. without pharmacological treatment and during stimulation (DBS condition),
3. during pharmacological treatment and without stimulation (DOPA condition),
4. during pharmacological treatment and stimulation (DOPA+DBS condition).
Eligibility Criteria
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Inclusion Criteria
* 18 to 75 years-old
* With idiopathic Parkinson's disease
* Having a STN-DBS with a PERCEPT™ for less than a year or being candidate for STN-DBS with the PERCEPT™ device (first-implantation)
* Able to perform the simple motor task
* Patients covered by a health insurance scheme
* Giving free, informed, written consent signed by the participant and the investigator.
Exclusion Criteria
* Be subject to a legal protection measure (curatorship, guardianship) or be placed under judicial protection.
* Being pregnant or breastfeeding
* Present a serious and/or decompensated somatic or psychiatric illness.
18 Years
75 Years
ALL
No
Sponsors
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Université de Bordeaux, IMN, UMR CNRS 5293
UNKNOWN
University Hospital, Bordeaux
OTHER
Responsible Party
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Locations
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Bordeaux University Hospital
Bordeaux, , France
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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CHUBX 2023/63
Identifier Type: -
Identifier Source: org_study_id
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