Subthalamic Nucleus Connectivity in Parkinson's Disease With Ultra-high Field Magnetic Resonance Imaging

NCT ID: NCT01981577

Last Updated: 2016-03-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-04-30

Brief Summary

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The purpose of this study is to investigate the segregation of the subthalamic nucleus into its motor and non-motor regions in patients with Parkinson's disease and healthy controls with the aid of ultra-high field magnetic resonance imaging.

Detailed Description

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Conditions

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Parkinson Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Patients with Parkinson's Disease

No interventions assigned to this group

Healthy volunteers

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

Both groups:

* Mental competence

Group 1:

* Parkinson's disease patients scheduled for deep brain stimulation surgery

Group 2:

* Age and gender matched volunteers

Exclusion Criteria

Both groups:

* Head injury
* Stroke
* Other neurological diseases other than Parkinson's disease
* Metallic prostheses or pacemaker in the subject's body or other contra indications for MRI

Group 1:

* Inability to abstain from dopaminergic drug use

Group 2:

* Parkinson's disease
* Use of medication affecting the central nervous system
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Netherlands Organisation for Scientific Research

OTHER_GOV

Sponsor Role collaborator

Maastricht University Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Yasin Temel, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Maastricht University Medical Center

Locations

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Maastricht University Medical Center

Maastricht, , Netherlands

Site Status RECRUITING

Countries

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Netherlands

Central Contacts

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Birgit R Plantinga, MSc.

Role: CONTACT

+31 43 3881033

Other Identifiers

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NL42613.068.13

Identifier Type: -

Identifier Source: org_study_id

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