Omega-3 Fatty Acid and Colorectal Adenoma

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

798 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-11-01

Study Completion Date

2024-02-21

Brief Summary

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Patients aged \>40 years who underwent elective colonoscopies were recruited from ten institutions. Patients with a history of colorectal cancer or long-term dietary interventions were excluded. Participants completed a food frequency questionnaire (FFQ) prior to endoscopy. FFQ data were analyzed using energy-, age-, sex-, and body mass index-adjusted models; the dietary supplemental omega-3 intake was analyzed separately. Colonoscopy outcome data, including the adenoma number, pathology, and location, were collected. Participants were stratified into omega-3 consumption quartiles to assess colorectal adenoma incidence trends using P for trend analysis.

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Detailed Description

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Conditions

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Colorectal Neoplasms Adenoma Colon

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Interventions

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Dietary intake of omega-3 fatty acid

Participants were stratified into omega-3 consumption quartiles to assess colorectal adenoma incidence trends

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* all patients aged more than 40 years of age, scheduled for elective colonoscopy.

Exclusion Criteria

* inflammatory bowel diseases
* history of colorectal neoplasms
* prior gastrointestinal surgery
* substance abuse including alcohol
* an inability to complete the survey due to emergency endoscopy
* cognitive impairments and those undergoing significant dietary modifications

Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No