GaMA Metric to Quantify Functional Importance of Various Upper Limb Prosthetic Devices

NCT ID: NCT06420687

Last Updated: 2025-03-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-04-20

Study Completion Date

2025-09-30

Brief Summary

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The goal of this study is to utilize the Gaze and Movement Assessment (GaMA) metric to assess the effect of different prosthetic components on compensatory movements used to complete activities of daily living.

Detailed Description

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Evaluating the benefit of new prosthetic components and control mechanisms can be challenging, as most validated outcome measures assess the time required to complete various tasks without assessing the quality of the movement or the specific DOF(s) activated to accomplish the task. There are no adequate methods to evaluate the impact of new technology. The functional outcome measures recommended by The Academy of Prosthetics and Orthotics Upper Limb Prosthetic Outcome Measures (ULPOM) committee, which provided recommendations for measuring functional effectiveness of prosthetic treatment, mainly focus on the time to complete the task rather than assessing the compensatory movements.

The Gaze and Movement Assessment (GaMA) is a new validated and standardized metric to quantify the functional characteristics of prosthesis use by quantifying motion (three dimensional angular kinematics), gaze behavior and performance during simulated real-world tasks. There are two tasks, the Cup Transfer Task and the Pasta Box Task, used with the GAMA testing hardware. The tasks require movements representing day-to-day functional requirements, while challenging typical prosthetic limitations such as reaching and transporting objects at varying heights and across the body and lack of wrist motion. Each task can be subdivided into specific phases of reaching, grasping, transporting and releasing objects. A performance aspect encourages the participant to work efficiently, and tasks are short to allow multiple repetitions within a reasonable testing time frame to assess performance consistency. By breaking down each task into movements (i.e., of the pasta box from one shelf to the next), and each movement into specific phases (reach, grasp, transport, and release), the investigators can examine these components individually. It is hypothesized that additional degrees-of-freedom (for example wrist flexion) may require more time but will reduce the compensatory movements required to complete the tasks.

The primary endpoint of the study is to quantify the effect of various prosthetics components on kinematics.

The secondary endpoint is to obtain normative data for the GaMA system and system validation.

Conditions

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Amputation Amputation, Traumatic Amputation; Traumatic, Hand Amputation; Traumatic, Limb

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

FACTORIAL

The GaMA metric will utilize motion capture and eye tracking hardware and software during the administration of functional tasks while research participants are using commercially available prosthetic devices and investigational prosthetic devices currently in development.
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Able-bodied participants

Participants without amputation were enrolled to collect normative data for system validation. Adhesive motion capture markers will be placed on both arms (upper arm, forearm, hand and finger tips), thoracic spine and sacrum. The participant wears a specialized headband/glasses with an attached camera for eye tracking. The participant will pick up and move objects of different shapes to and from various heights.

Group Type NO_INTERVENTION

No interventions assigned to this group

Transradial amputee participants

Individuals using their home prosthesis when available. Adhesive motion capture markers will be placed on both arms (upper arm, forearm, hand and finger tips), thoracic spine and sacrum. The participant will wear a headband with attached markers for eye tracking. The participant will pick up and move objects of different shapes to and from various heights.

Group Type ACTIVE_COMPARATOR

Clinically prescribed prosthesis

Intervention Type DEVICE

Clinically prescribed prosthesis:

Transradial amputee participants - Wrist rotation+1 dof hand

Individuals with transradial amputation fit with experimental prosthesis consisting of wrist rotation and one degree of freedom hand. Adhesive motion capture markers will be placed on both arms (upper arm, forearm, hand and finger tips), thoracic spine and sacrum. The participant will wear a headband with attached markers for eye tracking. The participant will pick up and move objects of different shapes to and from various heights.

Group Type EXPERIMENTAL

Experimental prosthesis - Wrist rotation + 1-DOF

Intervention Type DEVICE

1-DOF wrist rotation and1-DOF hand

Transradial amputee participants - Wrist rotation + wrist flexion +1 dof hand

Individuals with transradial amputation fit with experimental prosthesis consisting of wrist rotation, wrist flexion and one degree of freedom hand. Adhesive motion capture markers will be placed on both arms (upper arm, forearm, hand and finger tips), thoracic spine and sacrum. The participant will wear a headband with attached markers for eye tracking. The participant will pick up and move objects of different shapes to and from various heights.

Group Type EXPERIMENTAL

Experimental prosthesis - Wrist rotation + Wrist flexion +1-DOF

Intervention Type DEVICE

2-DOF wrist (rotation and flexion) and 1-DOF hand

Transradial amputee participants - Wrist rotation + multi degree freedom hand

Individuals with transradial amputation fit with experimental prosthesis consisting of wrist rotation and multi degree freedom hand. Adhesive motion capture markers will be placed on both arms (upper arm, forearm, hand and finger tips), thoracic spine and sacrum. The participant will wear a headband with attached markers for eye tracking. The participant will pick up and move objects of different shapes to and from various heights.

Group Type EXPERIMENTAL

Experimental prosthesis - Wrist rotation + Multi DOF hand

Intervention Type DEVICE

1-DOF wrist rotation and multi-DOF hand

Transradial amputee participants - Wrist rotation + wrist flexion + multi degree freedom hand

Individuals with transradial amputation fit with experimental prosthesis consisting of wrist rotation, wrist flexion and multi degree freedom hand. Adhesive motion capture markers will be placed on both arms (upper arm, forearm, hand and finger tips), thoracic spine and sacrum. The participant will wear a headband with attached markers for eye tracking. The participant will pick up and move objects of different shapes to and from various heights.

Group Type EXPERIMENTAL

Experimental prosthesis - Wrist rotation + wrist flexion + Multi DOF hand

Intervention Type DEVICE

2-DOF wrist (rotation and flexion) and multi-DOF hand

Interventions

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Clinically prescribed prosthesis

Clinically prescribed prosthesis:

Intervention Type DEVICE

Experimental prosthesis - Wrist rotation + 1-DOF

1-DOF wrist rotation and1-DOF hand

Intervention Type DEVICE

Experimental prosthesis - Wrist rotation + Wrist flexion +1-DOF

2-DOF wrist (rotation and flexion) and 1-DOF hand

Intervention Type DEVICE

Experimental prosthesis - Wrist rotation + Multi DOF hand

1-DOF wrist rotation and multi-DOF hand

Intervention Type DEVICE

Experimental prosthesis - Wrist rotation + wrist flexion + Multi DOF hand

2-DOF wrist (rotation and flexion) and multi-DOF hand

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* A unilateral upper limb amputation or absence below the elbow
* Ability to use a myoelectric prosthesis
* English Speaking

Exclusion Criteria

* Significant new injury that would prevent use of a prosthesis: The ability to consistently wear a prosthesis and perform activities of daily living and specific performance tasks is necessary to evaluate the relative benefits of the interventions.
* Cognitive impairment sufficient to adversely affect understanding of or compliance with study requirements, ability to communicate experiences, or ability to give informed consent: The ability to understand and comply with requirements of the study is essential in order for the study to generate useable, reliable data.
* Significant other comorbidity: Any other medical issues or injuries that would preclude completion of the study, use of the prostheses, or that would otherwise prevent acquisition of useable data by researchers
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Alberta

OTHER

Sponsor Role collaborator

Shirley Ryan AbilityLab

OTHER

Sponsor Role lead

Responsible Party

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Laura Miller

Team Scientist III

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Shirley Ryan AbilityLab

Chicago, Illinois, United States

Site Status

Countries

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United States

Other Identifiers

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STU00211352

Identifier Type: -

Identifier Source: org_study_id

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