Population-based Investigation of Aneurysm Incidence

NCT ID: NCT06412783

Last Updated: 2025-05-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

4711 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-10-01

Study Completion Date

2025-02-28

Brief Summary

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Most intracranial aneurysms are found accidentally in neurovascular imaging. And these inspection methods are limited by the problems of instrument fixation, radiation, time-consuming, contrast agent toxicity and so on. At present, blood test is an ideal alternative method for early diagnosis. Compared with imaging examination, it is economical, general screening and convenient. Blood test is simple to operate, easy to be accepted by patients, and less invasive. Early screening of aneurysms can be performed.

Detailed Description

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Conditions

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Intracranial Aneurysm

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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blood test group

Group Type EXPERIMENTAL

blood test

Intervention Type DIAGNOSTIC_TEST

performing blood tests on the participants for specific markers.

Interventions

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blood test

performing blood tests on the participants for specific markers.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Age 35-75
* Individuals with normal cognitive and communication abilities
* No serious complications, such as uncontrolled hypertension, diabetes or other chronic diseases that may affect the test results.
* Basic blood test is normal or close to normal range.

Exclusion Criteria

* Pregnancy
* Severe heart disease, renal insufficiency, liver dysfunction and other major diseases.
* In the past 6 months, there were strokes, or other types of intracranial tumors, infections and other diseases that may affect the screening results.
* There are metal implants, including dentures, pacemakers, etc.
* Using or recently used drugs that may affect blood biomarkers ( such as anticoagulant drugs, immunosuppressive agents, etc. ).
* There are serious mental illness or cognitive dysfunction, such as claustrophobia, unable to cooperate with the completion of the test.
* It is currently participating in other clinical trials or has participated in other clinical trials in the past 3 months.
Minimum Eligible Age

35 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Beijing Tiantan Hospital

OTHER

Sponsor Role lead

Responsible Party

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Wang Shuo

Director of Department of Cerebrovascular Neurosurgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Capital Medical University Affiliated Beijing Tiantan Hospital

Beijing, Beijing Municipality, China

Site Status

Countries

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China

Other Identifiers

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2021YFC2501103

Identifier Type: -

Identifier Source: org_study_id

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