Evaluation of 3D Surface Scanning for Virtual-CT Based Radiation Therapy Treatment Planning

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

26 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-19

Study Completion Date

2028-08-31

Brief Summary

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This study evaluates if three dimensional (3D) surface images can be used instead of the standard computed tomography (CT) scans for treatment planning in electron radiation therapy. 3D scanning has previously been used by several groups to design patient-specific devices to be 3D printed, and as has shown excellent agreement with CT obtained surfaces. Using 3D surface imaging instead of x-ray based CT, benefits include: no ionizing radiation used to produce images, shorter time between patient consultation and treatment, and ability to produce and evaluate patient-specific devices for electron therapy earlier in the treatment planning process. This study may help researchers learn how 3D surface scanning may be used to produce a virtual CT image of patient surfaces, and accurately replace traditional planning CT for treatment planning of electron based radiation therapy.

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Detailed Description

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PRIMARY OBJECTIVES:

I. Develop and benchmark the necessary software to convert a 3D scan to a virtual CT.

II. Compare the spatial accuracy of virtual CTs from 3D scans to the planning CT.

III. Compare radiation treatment plans based on the virtual CTs from aim 2 to treatment plans based on the actual planning CTs.

OUTLINE: This is an observational study.

Patients undergo 3D surface scans on study. Patient's medical records are also reviewed on study.

Conditions

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Hematopoietic and Lymphatic System Neoplasm Malignant Solid Neoplasm

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Observational (3D surface scans, medical records)

Patients undergo 3D surface scans on study. Patient's medical records are also reviewed on study.

Electronic Health Record Review

Intervention Type OTHER

Medical records reviewed

Three-Dimensional Imaging

Intervention Type PROCEDURE

Undergo 3D surface scans

Interventions

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Electronic Health Record Review

Medical records reviewed

Intervention Type OTHER

Three-Dimensional Imaging

Undergo 3D surface scans

Intervention Type PROCEDURE

Other Intervention Names

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3-D Imaging 3-Dimensional Imaging 3D Imaging Medical Imaging, Three Dimensional

Eligibility Criteria

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Inclusion Criteria

* Adults (18 years old or older)
* Capable of consent
* Receiving electron therapy and a planning CT scan
* Consent to two 3D surface scans of treatment area

Exclusion Criteria

* Pediatric patients
* Mentally incapable of study consent
* Receiving electron radiation for a breast cancer boost
* Receiving electrons for total skin electron therapy
* Patients with epilepsy or other seizure disorders

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No